Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi

doi:10.1021/np900595v

	Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi
	Feng, Tao 1,2; Cai, Xiang-Hai1 ; Liu, Ya-Ping 1,2; Li, Yan1 ; Wang, Yuan-Yuan 1; Luo, Xiao-Dong1
	2010
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	73 期号:1 页码:22-26
摘要	Nineteen monoterpenoid indole alkaloids including seven new ones, melodinines A-G (1-7), were isolated from Melodinus henryi. The structures of the new compounds were elucidated using spectroscopic methods, and the Structure of compound 4 was confirmed by single-crystal X-ray diffraction analysis. The known compounds were identified by comparing their spectroscopic data with those reported in the literature. All of the compounds were evaluated for cytotoxic activity against live human cancer cell lines, and compound 11 exhibited cytotoxicity against HL-60, SMMC-7721, A-549, and SK-BR-3 cells with IC(50) values of 2.0, 16.8, 25.9. and 24.7 mu M, respectively.
关键词	Anti-hiv Activity Var. Propinqua Unique Skeleton Lancifolia Micrantha Schiartane Chinensis
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI	10.1021/np900595v
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000273654000006
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4888
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,et al. Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(1):22-26.
APA	Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,Li, Yan,Wang, Yuan-Yuan,&Luo, Xiao-Dong.(2010).Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi.JOURNAL OF NATURAL PRODUCTS,73(1),22-26.
MLA	Feng, Tao,et al."Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi".JOURNAL OF NATURAL PRODUCTS 73.1(2010):22-26.

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