Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi
Feng, Tao1,2; Cai, Xiang-Hai1; Liu, Ya-Ping1,2; Li, Yan1; Wang, Yuan-Yuan1; Luo, Xiao-Dong1
2010
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume73Issue:1Pages:22-26
AbstractNineteen monoterpenoid indole alkaloids including seven new ones, melodinines A-G (1-7), were isolated from Melodinus henryi. The structures of the new compounds were elucidated using spectroscopic methods, and the Structure of compound 4 was confirmed by single-crystal X-ray diffraction analysis. The known compounds were identified by comparing their spectroscopic data with those reported in the literature. All of the compounds were evaluated for cytotoxic activity against live human cancer cell lines, and compound 11 exhibited cytotoxicity against HL-60, SMMC-7721, A-549, and SK-BR-3 cells with IC(50) values of 2.0, 16.8, 25.9. and 24.7 mu M, respectively.
KeywordAnti-hiv Activity Var. Propinqua Unique Skeleton Lancifolia Micrantha Schiartane Chinensis
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np900595v
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000273654000006
Citation statistics
Cited Times:60[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/4888
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,et al. Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(1):22-26.
APA Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,Li, Yan,Wang, Yuan-Yuan,&Luo, Xiao-Dong.(2010).Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi.JOURNAL OF NATURAL PRODUCTS,73(1),22-26.
MLA Feng, Tao,et al."Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi".JOURNAL OF NATURAL PRODUCTS 73.1(2010):22-26.
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