Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi
Feng, Tao1,2; Cai, Xiang-Hai1; Liu, Ya-Ping1,2; Li, Yan1; Wang, Yuan-Yuan1; Luo, Xiao-Dong1
2010
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号73期号:1页码:22-26
摘要Nineteen monoterpenoid indole alkaloids including seven new ones, melodinines A-G (1-7), were isolated from Melodinus henryi. The structures of the new compounds were elucidated using spectroscopic methods, and the Structure of compound 4 was confirmed by single-crystal X-ray diffraction analysis. The known compounds were identified by comparing their spectroscopic data with those reported in the literature. All of the compounds were evaluated for cytotoxic activity against live human cancer cell lines, and compound 11 exhibited cytotoxicity against HL-60, SMMC-7721, A-549, and SK-BR-3 cells with IC(50) values of 2.0, 16.8, 25.9. and 24.7 mu M, respectively.
关键词Anti-hiv Activity Var. Propinqua Unique Skeleton Lancifolia Micrantha Schiartane Chinensis
资助信息National Basic Research Program of China [2009CB522300]; Chinese Academy of Science
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np900595v
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000273654000006
引用统计
被引频次:57[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4888
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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GB/T 7714
Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,et al. Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(1):22-26.
APA Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,Li, Yan,Wang, Yuan-Yuan,&Luo, Xiao-Dong.(2010).Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi.JOURNAL OF NATURAL PRODUCTS,73(1),22-26.
MLA Feng, Tao,et al."Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi".JOURNAL OF NATURAL PRODUCTS 73.1(2010):22-26.
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