Potent alpha-glucosidase inhibitors from the roots of Panax japonicus C. A. Meyer var. major
Chan, Hsiu-Hui1; Sun, Han-Dong2; Reddy, Mopur Vijaya Bhaskar1; Wu, Tian-Shung1,3
2010-08-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号71期号:11-12页码:1360-1364
摘要Bioassay-guided fractionation of the CHCl(3) soluble portion of the roots of Panax japonicus C. A. Meyer var. major afforded an active fraction with inhibitory activity against baker's yeast alpha-glucosidase with an IC(50) value 1.02 mg/mL. Furthermore, the active fraction isolated contained three previously unreported polyacetylenes, designated panaxjapynes A-C, together with 11 other compounds, including four polyacetylenes, five phenolic compounds, a sesquiterpenoid, and a sterol glucoside. The structures of the compounds were elucidated by spectroscopic and chemical methods. Compared with the control acarbose (IC(50) 677.97 mu M), six compounds were shown to be more potent alpha-glucosidase inhibitors with IC(50) values in the range 22.21-217.68 mu M. Crown Copyright (C) 2010 Published by Elsevier Ltd. All rights reserved.
关键词Araliaceae PA.A. JA.oniC.s C. A. Meyer vA.. mA.or Zu-tziseng Polyacetylene Acarbose Alpha-glucosidase Inhibitors
资助信息National Science Council of Republic of China
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytochem.2010.04.013
收录类别SCI ; IC
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000280321000018
引用统计
被引频次:31[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4866
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Natl Cheng Kung Univ, Dept Chem, Tainan 70101, Taiwan
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
3.China Med Univ, Dept Pharm, Taichung 40402, Taiwan
推荐引用方式
GB/T 7714
Chan, Hsiu-Hui,Sun, Han-Dong,Reddy, Mopur Vijaya Bhaskar,et al. Potent alpha-glucosidase inhibitors from the roots of Panax japonicus C. A. Meyer var. major[J]. PHYTOCHEMISTRY,2010,71(11-12):1360-1364.
APA Chan, Hsiu-Hui,Sun, Han-Dong,Reddy, Mopur Vijaya Bhaskar,&Wu, Tian-Shung.(2010).Potent alpha-glucosidase inhibitors from the roots of Panax japonicus C. A. Meyer var. major.PHYTOCHEMISTRY,71(11-12),1360-1364.
MLA Chan, Hsiu-Hui,et al."Potent alpha-glucosidase inhibitors from the roots of Panax japonicus C. A. Meyer var. major".PHYTOCHEMISTRY 71.11-12(2010):1360-1364.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201202230001.pdf(211KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chan, Hsiu-Hui]的文章
[Sun, Han-Dong]的文章
[Reddy, Mopur Vijaya Bhaskar]的文章
百度学术
百度学术中相似的文章
[Chan, Hsiu-Hui]的文章
[Sun, Han-Dong]的文章
[Reddy, Mopur Vijaya Bhaskar]的文章
必应学术
必应学术中相似的文章
[Chan, Hsiu-Hui]的文章
[Sun, Han-Dong]的文章
[Reddy, Mopur Vijaya Bhaskar]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。