| 7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii | |
Tian, Li-Wen1,2; Pei, Ying3; Zhang, Ying-Jun1 ; Wang, Yi-Fei3; Yang, Chong-Ren1
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| 2009-06-01 | |
| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
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| ISSN | 0163-3864 |
| 卷号 | 72期号:6页码:1057-1060 |
| 摘要 | Five new 7-O-methylkaempferol and -quercetin glycosides, namely, nervili fordins A-E (1-5), were isolated from the whole plant of Nervilia fordii, together with seven known flavonoids (6, 7, and 9-13) and one known coumarin (8). Their structures were elucidated on the basis of extensive spectroscopic analyses, including HSQC, HMBC, ROESY, and chemical methods. Compounds 1-3 and 6-13 were evaluated for their anti-herpes simplex virus 1 (HSV-1) activity and cytotoxicity on African green monkey kidney cells (Vero cells) in vitro. Of the tested compounds, only esculetin (8) exhibited antiviral activity against HSV-1, while the aglycones (11-13) showed stronger cytotoxicity on Vero cells than their glycosides (1-3, 6, and 7). |
| 关键词 | Sesquiterpene Lactones Pubescens Terpenoids |
| 学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1021/np800760p |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000267432600013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/4806 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 10039, Peoples R China 3.Jinan Univ, Guangzhou 510632, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tian, Li-Wen,Pei, Ying,Zhang, Ying-Jun,et al. 7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(6):1057-1060. |
| APA | Tian, Li-Wen,Pei, Ying,Zhang, Ying-Jun,Wang, Yi-Fei,&Yang, Chong-Ren.(2009).7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii.JOURNAL OF NATURAL PRODUCTS,72(6),1057-1060. |
| MLA | Tian, Li-Wen,et al."7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii".JOURNAL OF NATURAL PRODUCTS 72.6(2009):1057-1060. |
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