7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii
Tian, Li-Wen1,2; Pei, Ying3; Zhang, Ying-Jun1; Wang, Yi-Fei3; Yang, Chong-Ren1
2009-06-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号72期号:6页码:1057-1060
摘要Five new 7-O-methylkaempferol and -quercetin glycosides, namely, nervili fordins A-E (1-5), were isolated from the whole plant of Nervilia fordii, together with seven known flavonoids (6, 7, and 9-13) and one known coumarin (8). Their structures were elucidated on the basis of extensive spectroscopic analyses, including HSQC, HMBC, ROESY, and chemical methods. Compounds 1-3 and 6-13 were evaluated for their anti-herpes simplex virus 1 (HSV-1) activity and cytotoxicity on African green monkey kidney cells (Vero cells) in vitro. Of the tested compounds, only esculetin (8) exhibited antiviral activity against HSV-1, while the aglycones (11-13) showed stronger cytotoxicity on Vero cells than their glycosides (1-3, 6, and 7).
关键词Sesquiterpene Lactones Pubescens Terpenoids
资助信息NSFC [U0632010]; Chinese Academy of Sciences [0807E21211]
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np800760p
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000267432600013
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4806
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 10039, Peoples R China
3.Jinan Univ, Guangzhou 510632, Guangdong, Peoples R China
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GB/T 7714
Tian, Li-Wen,Pei, Ying,Zhang, Ying-Jun,et al. 7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(6):1057-1060.
APA Tian, Li-Wen,Pei, Ying,Zhang, Ying-Jun,Wang, Yi-Fei,&Yang, Chong-Ren.(2009).7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii.JOURNAL OF NATURAL PRODUCTS,72(6),1057-1060.
MLA Tian, Li-Wen,et al."7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii".JOURNAL OF NATURAL PRODUCTS 72.6(2009):1057-1060.
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