Monoterpenoid Indole Alkaloids from Alstonia yunnanensis
Feng, Tao1,2; Li, Yan1; Cai, Xiang-Hai1; Gong, Xun1; Liu, Ya-Ping1,2; Zhang, Rong-Ting1,2; Zhang, Xiang-Yun1,2; Tan, Qin-Gang1,2; Luo, Xiao-Dong1
2009-10-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号72期号:10页码:1836-1841
摘要Eight new monoterpenoid indole alkaloids, alstoyunines A-H (1-8), along with 17 known analogues, were isolated from Alstonia yunnanensis. The structures of. the new alkaloids were established by means of extensive spectroscopic methods. Alstoyunines C (3), E (5), and F (6) showed selective inhibition of Cox-2 (>75%). Alstoyunine F (6) showed weak cytotoxicity against the human myeloid leukemia HL-60 (IC(50) = 3.89 mu M) and hepatocellular carcinoma SMMC-7721 (IC(50) = 21.73 mu M) cell lines.
关键词Cultures Antifungal Metabolite Couplings
资助信息National Basic Research Program of China [2009CB522300]; Chinese Academy of Science [KZCX2-XB2-15]
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np900374s
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000271950400017
引用统计
被引频次:39[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4794
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Feng, Tao,Li, Yan,Cai, Xiang-Hai,et al. Monoterpenoid Indole Alkaloids from Alstonia yunnanensis[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(10):1836-1841.
APA Feng, Tao.,Li, Yan.,Cai, Xiang-Hai.,Gong, Xun.,Liu, Ya-Ping.,...&Luo, Xiao-Dong.(2009).Monoterpenoid Indole Alkaloids from Alstonia yunnanensis.JOURNAL OF NATURAL PRODUCTS,72(10),1836-1841.
MLA Feng, Tao,et al."Monoterpenoid Indole Alkaloids from Alstonia yunnanensis".JOURNAL OF NATURAL PRODUCTS 72.10(2009):1836-1841.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201202230037.pdf(483KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Feng, Tao]的文章
[Li, Yan]的文章
[Cai, Xiang-Hai]的文章
百度学术
百度学术中相似的文章
[Feng, Tao]的文章
[Li, Yan]的文章
[Cai, Xiang-Hai]的文章
必应学术
必应学术中相似的文章
[Feng, Tao]的文章
[Li, Yan]的文章
[Cai, Xiang-Hai]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。