Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata
He, Fei1,4; Xiao, Wei-Lie1; Pu, Jian-Xin1; Wu, Ying-Li2,3; Zhang, Hai-Bo1,4; Li, Xiao-Nian1,4; Zhao, Yong1; Yang, Li-Bin1; Chen, Guo-Qiang2,3; Sun, Han-Dong1
2009-07-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号70期号:11-12页码:1462-1466
摘要Five (1-5) ent-kaurane diterpenoids and 17 other known ones, were isolated from the leaves and stems of Isodon sinuolata. Their structures were determined on the basis of spectroscopic methods including 1D and 2D NMR spectroscopic analysis. All compounds were evaluated for cytotoxicity against a small panel of cell lines. Some compounds exhibited significant cytotoxicity. (C) 2009 Elsevier Ltd. All rights reserved.
关键词Isodon Sinuolata Labiatae Diterpenoids Cytotoxicity
资助信息National Natural Science Foundation of China [30772637]; NSFC-Joint Foundation of Yunnan Province [U0832602]; Major State Basic Research Development Program of China [2009CB522303, 2009CB940900]; National Science Foundation of Yunnan Province [2008CD162]
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytochem.2009.07.037
收录类别SCI ; IC
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000271177600017
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4786
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Dept Pathophysiol, Shanghai 200025, Peoples R China
3.Chinese Acad Sci, Key Lab Cell Differentiat & Apoptosis, Shanghai 200025, Peoples R China
4.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
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He, Fei,Xiao, Wei-Lie,Pu, Jian-Xin,et al. Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata[J]. PHYTOCHEMISTRY,2009,70(11-12):1462-1466.
APA He, Fei.,Xiao, Wei-Lie.,Pu, Jian-Xin.,Wu, Ying-Li.,Zhang, Hai-Bo.,...&Sun, Han-Dong.(2009).Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata.PHYTOCHEMISTRY,70(11-12),1462-1466.
MLA He, Fei,et al."Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata".PHYTOCHEMISTRY 70.11-12(2009):1462-1466.
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