Spirostanol tetraglycosides from Ypsilandra thibetica
Lu, Yi1,2; Chen, Chang-Xiang1; Ni, Wei1; Hua, Yan2; Liu, Hai-Yang1
Source PublicationSTEROIDS
AbstractPhytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained five new spirostane glycosides, ypsilandrosides H-L (1-5), and a known saponin polyphylloside III (6). Among them, 1 and 2 are the first spirostane glycosides which possess novel 5(6 -> 7) abeo-steroidal aglycones. Compounds 3 and 4 are rare saponins whose aglycones contain a hydroxyl group at C-7. Their structures were elucidated on the basis of MS, 1D and 2D NMR spectroscopic analysis and chemical evidences. The isolated compounds were evaluated for their cytotoxic activity on five tumor cell lines. (C) 2010 Elsevier Inc. All rights reserved.
KeywordYpsilandra Thibetica Liliaceae Spirostanol Saponins Ypsilandrosides H-l
Subject AreaBiochemistry & Molecular Biology ; Endocrinology & Metabolism
Indexed BySCI ; IC
WOS Research AreaBiochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS SubjectBiochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS IDWOS:000281932500025
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Cited Times:15[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.SW Forestry Univ, Fac Nat Resources, Kunming 650224, Peoples R China
Recommended Citation
GB/T 7714
Lu, Yi,Chen, Chang-Xiang,Ni, Wei,et al. Spirostanol tetraglycosides from Ypsilandra thibetica[J]. STEROIDS,2010,75(12):982-987.
APA Lu, Yi,Chen, Chang-Xiang,Ni, Wei,Hua, Yan,&Liu, Hai-Yang.(2010).Spirostanol tetraglycosides from Ypsilandra thibetica.STEROIDS,75(12),982-987.
MLA Lu, Yi,et al."Spirostanol tetraglycosides from Ypsilandra thibetica".STEROIDS 75.12(2010):982-987.
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