Kansuinone, a novel euphane-type triterpene from Euphorbia kansui

doi:10.1016/j.tetlet.2010.09.099

	Kansuinone, a novel euphane-type triterpene from Euphorbia kansui
	Guo, Jie 1,2; He, Hong-Ping 2; Fang, Xin 2; Di, Ying-Tong2 ; Li, Shun-Lin 2; Zhang, Zhen 2; Leng, Ying 3; Hua, Hui-Ming 1; Hao, Xiao-Jiang2
	2010-12-01
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	51 期号:48 页码:6286-6289
摘要	Kansuinone (1), a rearranged euphane triterpenoid containing a spiro [5,61 ring system, was isolated from the roots of Euphorbia kansui. Its structure and stereochemistry were elucidated on the basis of spectro-scopic, CD, and computational methods. Kansuinone (1) exhibited inhibitory activity against human and mouse 11 beta-HSD1 (11 beta-hydroxysteroid dehydrogenase type 1), with IC(50) values of 1.12 and 1.08 mu M, respectively. (C) 2010 Elsevier Ltd. All rights reserved.
关键词	Euphorbia Kansui Euphane-type Triterpene Structure Elucidation 11 Beta-hsd1 Inhibitory Activity
学科领域	Chemistry, Organic
DOI	10.1016/j.tetlet.2010.09.099
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000284303200021
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4306
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Guo, Jie,He, Hong-Ping,Fang, Xin,et al. Kansuinone, a novel euphane-type triterpene from Euphorbia kansui[J]. TETRAHEDRON LETTERS,2010,51(48):6286-6289.
APA	Guo, Jie.,He, Hong-Ping.,Fang, Xin.,Di, Ying-Tong.,Li, Shun-Lin.,...&Hao, Xiao-Jiang.(2010).Kansuinone, a novel euphane-type triterpene from Euphorbia kansui.TETRAHEDRON LETTERS,51(48),6286-6289.
MLA	Guo, Jie,et al."Kansuinone, a novel euphane-type triterpene from Euphorbia kansui".TETRAHEDRON LETTERS 51.48(2010):6286-6289.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
201201060026.pdf（502KB）			开放获取	--	浏览下载