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题名: Novel polyisoprenylated benzophenone derivatives from Garcinia paucinervis
作者: Gao, Xue-Mei2; Yu, Ting1; Lai, Fanny Shuk Fan2; Pu, Jian-Xin3; Qiao, Chun-Feng2; Zhou, Yan2; Liu, Xin2; Song, Jing-Zheng2; Luo, Kathy Qian1; Xu, Hong-Xi2
刊名: TETRAHEDRON LETTERS
关键词: Garcinia paucinervis ; Benzophenone ; Cytotoxiciry ; HeLa cell
英文摘要: Four novel polyisoprenylated benzophenone derivatives, paucinones A-D (1-4), were isolated from the leaves of the plant Garcinia paucinervis. Paucinones A-C (1-3) contained an unexpected cyclohexane-spiro-tetrahydrofuran moiety. A 1-methylene-3,3-dimethylcyclohexane group never reported before was found in the structure of paucinone D (4). The structures of these compounds were elucidated with spectroscopic evidences. The relative stereochemistries of 1-4 were determined by NOESY correlations. These compounds showed significant cytotoxicities against HeLa cells. (C) 2010 Elsevier Ltd. All rights reserved.
出版日期: 2010-05-05
卷号: 51, 期号:18, 页码:2442-2446
DOI标识: 10.1016/j.tetlet.2010.02.147
语种: 英语
ISSN号: 0040-4039
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4302
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Nanyang Technol Univ, Sch Chem & Biomed Engn, Div Bioengn, Singapore 637457, Singapore
2.Hong Kong Jockey Club Inst Chinese Med, Chinese Med Lab, Shatin, Hong Kong, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China

Recommended Citation:
Gao, XM; Yu, T; Lai, FSF; Pu, JX; Qiao, CF; Zhou, Y; Liu, X; Song, JZ; Luo, KQ; Xu, HX.Novel polyisoprenylated benzophenone derivatives from Garcinia paucinervis,TETRAHEDRON LETTERS,2010,51(18):2442-2446
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