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题名: Schilancidilactones A and B: two novel tetranortriterpenoids with an unprecedented skeleton from Schisandra lancifolia
作者: Luo, Xiao1, 7; Chang, Ying2; Zhang, Xing-Jie3, 4; Pu, Jian-Xin1; Gao, Xue-Mei1; Wu, Ying-Li5, 6; Wang, Rui-Rui3, 4; Xiao, Wei-Lie1; Zheng, Yong-Tang3, 4; Lu, Yang2; Chen, Guo-Qiang5, 6; Zheng, Qi-Tai2; null(孙汉董)1
刊名: TETRAHEDRON LETTERS
关键词: Schisandra lancifolia ; Schilancidilactones A and B ; Tetranortriterpenoid ; Anti-HIV activity
英文摘要: Schilancidilactones A (1) and B (2). two novel tetranortriterpenoids possessing an unprecedented skeleton, have been isolated from the stems of Schisandra lancifolia. Their structures were elucidated on the basis of extensive spectroscopic analysis. The relative configurations of 1 were further determined by single-crystal X-ray crystallography. Compounds 1 and 2 were tested for their cytotoxicity against four tumor cell lines NB4, A549, SH-SY5Y, and PC-3, and compound I was further tested for its anti-HIV-1 activity. (C) 2009 Elsevier Ltd. All rights reserved.
出版日期: 2009-10-28
卷号: 50, 期号:43, 页码:5962-5964
DOI标识: 10.1016/j.tetlet.2009.08.051
语种: 英语
ISSN号: 0040-4039
资助信息: NSFC [30830115, 20802082]; Chinese Academy of Sciences [KSCX1-YW-R-24]; 973 Program [2009CB522303]; Scientific and Technological projects of China [2009ZX09501-029]; Yong Academic and Technical Leader Rising Foundation of Yunnan Province [2006PY01-47]; Natural Science Foundation of Yunnan Province [2005XY04, 2006130042Q]
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4296
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
4.Chinese Acad Sci, Chinese Acad Sci & Yunnan Prov, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
5.Shanghai Jiao Tong Univ, Dept Pathophysiol, Chinese Minist Educ, Sch Med, Shanghai 200025, Peoples R China
6.Shanghai Jiao Tong Univ, Key Lab Cell Differentiat & Apoptosis, Chinese Minist Educ, Sch Med, Shanghai 200025, Peoples R China
7.Chinese Acad Sci, Grad Sch, Beijing 10039, Peoples R China

Recommended Citation:
Luo, X; Chang, Y; Zhang, XJ; Pu, JX; Gao, XM; Wu, YL; Wang, RR; Xiao, WL; Zheng, YT; Lu, Y; Chen, GQ; Zheng, QT; Sun, HD.Schilancidilactones A and B: two novel tetranortriterpenoids with an unprecedented skeleton from Schisandra lancifolia,TETRAHEDRON LETTERS,2009,50(43):5962-5964
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