Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid from Melodinus tenuicaudatus
Feng, Tao1,2; Li, Yan1; Liu, Ya-Ping1,2; Cai, Xiang-Hai1; Wang, Yuan-Yuan1; Luo, Xiao-Dong1
2010-03-05
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号12期号:5页码:968-971
摘要Melotenine A (1), an unprecedented skeleton with a 6/5/5/6/7 pentacyclic rearranged ring system, was isolated from Melodinus tenuicaudatus. The structure was elucidated by means of spectroscopic methods and further confirmed by the single-crystal X-ray diffraction analysis. A possible biogenesis was also proposed. Melotenine A exhibited potential inhibition against five human cancer cell lines.
关键词Aspidosperma Alkaloids Alstonia-scholaris Rearrangement Core
资助信息National Basic Research Program of China [2009CB522300]; Chinese Academy of Sciences [KSCX2-YW-R-202]; National Natural Science Foundation of China
学科领域Chemistry, Organic
DOI10.1021/ol1000022
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000274841800019
引用统计
被引频次:39[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4274
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Feng, Tao,Li, Yan,Liu, Ya-Ping,et al. Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid from Melodinus tenuicaudatus[J]. ORGANIC LETTERS,2010,12(5):968-971.
APA Feng, Tao,Li, Yan,Liu, Ya-Ping,Cai, Xiang-Hai,Wang, Yuan-Yuan,&Luo, Xiao-Dong.(2010).Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid from Melodinus tenuicaudatus.ORGANIC LETTERS,12(5),968-971.
MLA Feng, Tao,et al."Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid from Melodinus tenuicaudatus".ORGANIC LETTERS 12.5(2010):968-971.
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