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题名: Chemical Constituents from the Leaves and Stems of Schisandra lancifolia
作者: Xiao, Wei-Lie1; Yang, Liu-Meng2, 3; Zhang, Hai-Bo1, 4; Xue, Yong-Bo1, 4; Yang, Guang-Yu1, 5; Pu, Jian-Xin1; Wang, Rui-Rui2, 3; Zheng, Yong-Tang2, 3; null(孙汉董)1
刊名: CHEMICAL & PHARMACEUTICAL BULLETIN
关键词: nortriterpenoid ; lignan ; Schisandra lancifolia ; anti-human immunodeficiency virus-1 activity
英文摘要: A new nortriterpenoid, 20-hydroxymicrandilactone D (1) and a novel lignan glycoside, lancilignanside A (2) were isolated from leaves and stems of Schisandra lancifolia, together with three known nortriterpenoids (3-5) and nine known phenolics (6-14). The structures of new compounds 1 and 2 were determined by detailed analysis of their 1D and 2D NMR spectra, and chemical evidences. In addition, compounds 1-2, 6-7, and 9-11 showed anti-human immunodeficiency virus (HIV)-1 activities with 50% effective concentration (EC50) in the range of 3.0-99.0 mu g/ml. Compound 12 was not bioactive in this assay with EC50 more than 200 mu g/ml.
出版日期: 2010-06-01
卷号: 58, 期号:6, 页码:852-855
语种: 英语
ISSN号: 0009-2363
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4124
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
3.Chinese Acad Sci, Lab Mol Immunopharmacol, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
5.Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 6501064, Yunnan, Peoples R China

Recommended Citation:
Xiao, WL; Yang, LM; Zhang, HB; Xue, YB; Yang, GY; Pu, JX; Wang, RR; Zheng, YT; Sun, HD.Chemical Constituents from the Leaves and Stems of Schisandra lancifolia,CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(6):852-855
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