Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans

	Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans
	Jiang, Meng-Yuan 1,2; Zhang, Ling 1,2; Dong, Ze-Jun1 ; Yang, Zhu-Liang1 ; Leng, Ying 3; Liu, Ji-Kai 1
	2010
发表期刊	CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN	0009-2363
卷号	58 期号:1 页码:113-116
摘要	Three new metabolites, vibralactones D-F (1-3) were isolated from cultures of the basidiomycete Boreostereum vibrans. The relative configuration of I was established on the basis of X-ray diffraction analysis, while the absolute configurations of 1-3 were assigned using a modified Mosher's method. Compound I showed weak inhibitory activities against isozymes of 11 beta-hydroxysteroid dehydrogenases (HSD) with IC50 values of 85.7 mu M (human HSD1), 295.2 mu M (mouse HSD1), and 87.1 mu M (human HSD2).
关键词	Vibralactone 11 Beta-hydroxysteroid Dehydrogenase Activity Boreostereum Vibrans
学科领域	Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000273168400022
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4114
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Meng-Yuan,Zhang, Ling,Dong, Ze-Jun,et al. Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(1):113-116.
APA	Jiang, Meng-Yuan,Zhang, Ling,Dong, Ze-Jun,Yang, Zhu-Liang,Leng, Ying,&Liu, Ji-Kai.(2010).Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans.CHEMICAL & PHARMACEUTICAL BULLETIN,58(1),113-116.
MLA	Jiang, Meng-Yuan,et al."Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans".CHEMICAL & PHARMACEUTICAL BULLETIN 58.1(2010):113-116.

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