| Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans | |
Jiang, Meng-Yuan1,2; Zhang, Ling1,2; Dong, Ze-Jun1 ; Yang, Zhu-Liang1; Leng, Ying3; Liu, Ji-Kai1
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| 2010 | |
| 发表期刊 | CHEMICAL & PHARMACEUTICAL BULLETIN
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| ISSN | 0009-2363 |
| 卷号 | 58期号:1页码:113-116 |
| 摘要 | Three new metabolites, vibralactones D-F (1-3) were isolated from cultures of the basidiomycete Boreostereum vibrans. The relative configuration of I was established on the basis of X-ray diffraction analysis, while the absolute configurations of 1-3 were assigned using a modified Mosher's method. Compound I showed weak inhibitory activities against isozymes of 11 beta-hydroxysteroid dehydrogenases (HSD) with IC50 values of 85.7 mu M (human HSD1), 295.2 mu M (mouse HSD1), and 87.1 mu M (human HSD2). |
| 关键词 | Vibralactone 11 Beta-hydroxysteroid Dehydrogenase Activity Boreostereum Vibrans |
| 学科领域 | Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000273168400022 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/4114 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Meng-Yuan,Zhang, Ling,Dong, Ze-Jun,et al. Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(1):113-116. |
| APA | Jiang, Meng-Yuan,Zhang, Ling,Dong, Ze-Jun,Yang, Zhu-Liang,Leng, Ying,&Liu, Ji-Kai.(2010).Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans.CHEMICAL & PHARMACEUTICAL BULLETIN,58(1),113-116. |
| MLA | Jiang, Meng-Yuan,et al."Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans".CHEMICAL & PHARMACEUTICAL BULLETIN 58.1(2010):113-116. |
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