| Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides | |
Chen, Xuan-Qin1,2; Li, Yan1 ; Cheng, Xiao1; Wang, Kou1,2; He, Juan1,2; Pan, Zheng-Hong1,2; Li, Ming-Ming1,2; Peng, Li-Yan1; Xu, Gang1; Zhao, Qin-Shi1
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| 2010 | |
| 发表期刊 | CHEMISTRY & BIODIVERSITY
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| ISSN | 1612-1872 |
| 卷号 | 7期号:1页码:196-204 |
| 摘要 | Two new C(30)-epimeric polycyclic polyprenylated acylphloroglucinols (PPAPs), named uralodins B and C (1 and 2, resp.), were isolated from the aerial parts of Hypericum henryi subsp. uraloides together with two new chromone glucosides. urachromones A and B (3 and 4, resp.), as well as 16 known compounds. Their structures were established by extensive NMR techniques and MS analysis. The epimers 1 and 2 always behaved like a single compound when examined by TLC, and were separated by HPLC. Their configuration was distinguished by comparative analysis of the NMR data with known analogues together with the ROESY experiment. All the isolated PPAPs were evaluated for their cytotoxic activities against HepG2, SGC7901, HL-60, and K562 cell lines. Compound 1 showed modest cytotoxic activities against SGC7901 and HL-60 cell lines, and 2 showed modest cytotoxic activities against HepG2, SGC7901, HL-60, and K562 cell lines. |
| 关键词 | 2 Polyisoprenylated Benzophenones St Johns Wort Natural-products Cuban Propolis Derivatives Xanthones Hyperforin Glycosides Japonicum Assays |
| 学科领域 | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000274264000013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/4054 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xuan-Qin,Li, Yan,Cheng, Xiao,et al. Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides[J]. CHEMISTRY & BIODIVERSITY,2010,7(1):196-204. |
| APA | Chen, Xuan-Qin.,Li, Yan.,Cheng, Xiao.,Wang, Kou.,He, Juan.,...&Zhao, Qin-Shi.(2010).Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides.CHEMISTRY & BIODIVERSITY,7(1),196-204. |
| MLA | Chen, Xuan-Qin,et al."Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides".CHEMISTRY & BIODIVERSITY 7.1(2010):196-204. |
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