Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides
Chen, Xuan-Qin1,2; Li, Yan1; Cheng, Xiao1; Wang, Kou1,2; He, Juan1,2; Pan, Zheng-Hong1,2; Li, Ming-Ming1,2; Peng, Li-Yan1; Xu, Gang1; Zhao, Qin-Shi1
2010
发表期刊CHEMISTRY & BIODIVERSITY
ISSN1612-1872
卷号7期号:1页码:196-204
摘要Two new C(30)-epimeric polycyclic polyprenylated acylphloroglucinols (PPAPs), named uralodins B and C (1 and 2, resp.), were isolated from the aerial parts of Hypericum henryi subsp. uraloides together with two new chromone glucosides. urachromones A and B (3 and 4, resp.), as well as 16 known compounds. Their structures were established by extensive NMR techniques and MS analysis. The epimers 1 and 2 always behaved like a single compound when examined by TLC, and were separated by HPLC. Their configuration was distinguished by comparative analysis of the NMR data with known analogues together with the ROESY experiment. All the isolated PPAPs were evaluated for their cytotoxic activities against HepG2, SGC7901, HL-60, and K562 cell lines. Compound 1 showed modest cytotoxic activities against SGC7901 and HL-60 cell lines, and 2 showed modest cytotoxic activities against HepG2, SGC7901, HL-60, and K562 cell lines.
关键词2 Polyisoprenylated Benzophenones St Johns Wort Natural-products Cuban Propolis Derivatives Xanthones Hyperforin Glycosides Japonicum Assays
学科领域Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
WOS类目Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号WOS:000274264000013
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4054
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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GB/T 7714
Chen, Xuan-Qin,Li, Yan,Cheng, Xiao,et al. Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides[J]. CHEMISTRY & BIODIVERSITY,2010,7(1):196-204.
APA Chen, Xuan-Qin.,Li, Yan.,Cheng, Xiao.,Wang, Kou.,He, Juan.,...&Zhao, Qin-Shi.(2010).Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides.CHEMISTRY & BIODIVERSITY,7(1),196-204.
MLA Chen, Xuan-Qin,et al."Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides".CHEMISTRY & BIODIVERSITY 7.1(2010):196-204.
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