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题名: Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides
作者: Chen, Xuan-Qin1, 2; null(李艳)1; Cheng, Xiao1; Wang, Kou1, 2; He, Juan1, 2; Pan, Zheng-Hong1, 2; Li, Ming-Ming1, 2; Peng, Li-Yan1; null(许刚)1; null(赵勤实)1
刊名: CHEMISTRY & BIODIVERSITY
关键词: 2 POLYISOPRENYLATED BENZOPHENONES ; ST JOHNS WORT ; NATURAL-PRODUCTS ; CUBAN PROPOLIS ; DERIVATIVES ; XANTHONES ; HYPERFORIN ; GLYCOSIDES ; JAPONICUM ; ASSAYS
英文摘要: Two new C(30)-epimeric polycyclic polyprenylated acylphloroglucinols (PPAPs), named uralodins B and C (1 and 2, resp.), were isolated from the aerial parts of Hypericum henryi subsp. uraloides together with two new chromone glucosides. urachromones A and B (3 and 4, resp.), as well as 16 known compounds. Their structures were established by extensive NMR techniques and MS analysis. The epimers 1 and 2 always behaved like a single compound when examined by TLC, and were separated by HPLC. Their configuration was distinguished by comparative analysis of the NMR data with known analogues together with the ROESY experiment. All the isolated PPAPs were evaluated for their cytotoxic activities against HepG2, SGC7901, HL-60, and K562 cell lines. Compound 1 showed modest cytotoxic activities against SGC7901 and HL-60 cell lines, and 2 showed modest cytotoxic activities against HepG2, SGC7901, HL-60, and K562 cell lines.
出版日期: 2010
卷号: 7, 期号:1, 页码:196-204
语种: 英语
ISSN号: 1612-1872
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4054
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

Recommended Citation:
Chen, XQ; Li, Y; Cheng, X; Wang, K; He, J; Pan, ZH; Li, MM; Peng, LY; Xu, G; Zhao, QS.Polycyclic Polyprenylated Acylphloroglucinols and Chromone O-Glucosides from Hypericum henryi subsp uraloides,CHEMISTRY & BIODIVERSITY,2010,7(1):196-204
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