Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells | |
Yang, Xian-Wen1,2; He, Hong-Ping1; Du, Zhi-Zhi1; Liu, Hai-Yang1; Di, Ying-Tong1; Ma, Yan-Lin3; Wang, Fang3; Lin, Hua3; Zuo, Yi-Qing3; Li, Ling3; Hao, Xiao-Jiang1 | |
2009 | |
发表期刊 | CHEMISTRY & BIODIVERSITY |
ISSN | 1612-1872 |
卷号 | 6期号:4页码:540-550 |
摘要 | Eight new lignan glucosides, tarennanosides A-H (1-8, resp.), were isolated from the whole plant of Tarenna attenuata, together with three known compounds, fernandoside, (-)-lyoniresinol, and (-)isolariciresinol. The planar structures of new compounds were elucidated mainly by analysis of physical and spectroscopic data, and the absolute configurations were determined by acid hydrolysis as well as CD spectroscopy. Compounds I and 2 exhibited potent antioxidant activities against H2O2-induced impairment in PC12 cells. Preliminary mechanism study by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method showed that these two compounds could act as radical scavengers. |
关键词 | Constituents Glycosides Bark |
学科领域 | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000265475200011 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/4052 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China 3.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China |
推荐引用方式 GB/T 7714 | Yang, Xian-Wen,He, Hong-Ping,Du, Zhi-Zhi,et al. Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells[J]. CHEMISTRY & BIODIVERSITY,2009,6(4):540-550. |
APA | Yang, Xian-Wen.,He, Hong-Ping.,Du, Zhi-Zhi.,Liu, Hai-Yang.,Di, Ying-Tong.,...&Hao, Xiao-Jiang.(2009).Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells.CHEMISTRY & BIODIVERSITY,6(4),540-550. |
MLA | Yang, Xian-Wen,et al."Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells".CHEMISTRY & BIODIVERSITY 6.4(2009):540-550. |
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