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题名: Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells
作者: Yang, Xian-Wen1, 2; He, Hong-Ping1; null(杜芝芝)1; null(刘海洋)1; Di, Ying-Tong1; Ma, Yan-Lin3; Wang, Fang3; Lin, Hua3; Zuo, Yi-Qing3; Li, Ling3; null(郝小江)1
刊名: CHEMISTRY & BIODIVERSITY
关键词: CONSTITUENTS ; GLYCOSIDES ; BARK
英文摘要: Eight new lignan glucosides, tarennanosides A-H (1-8, resp.), were isolated from the whole plant of Tarenna attenuata, together with three known compounds, fernandoside, (-)-lyoniresinol, and (-)isolariciresinol. The planar structures of new compounds were elucidated mainly by analysis of physical and spectroscopic data, and the absolute configurations were determined by acid hydrolysis as well as CD spectroscopy. Compounds I and 2 exhibited potent antioxidant activities against H2O2-induced impairment in PC12 cells. Preliminary mechanism study by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method showed that these two compounds could act as radical scavengers.
出版日期: 2009
卷号: 6, 期号:4, 页码:540-550
语种: 英语
收录类别: SCI
学科分类: Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
ISSN号: 1612-1872
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4052
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
3.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China

Recommended Citation:
Yang, XW; He, HP; Du, ZZ; Liu, HY; Di, YT; Ma, YL; Wang, F; Lin, H; Zuo, YQ; Li, L; Hao, XJ.Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells,CHEMISTRY & BIODIVERSITY,2009,6(4):540-550
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