Collective formal synthesis of (+/-)-rhynchophylline and homologues
Xu, Jun1; Shao, Li-Dong1; Shi, Xin1,2; Ren, Jian1,2; Xia, Chengfeng1; Zhao, Qin-Shi1
2016
Source PublicationRSC ADVANCES
Volume6Issue:68Pages:63131-63135
AbstractA collective formal synthesis approach to bioactive oxindole alkaloids, including (+/-)-rhynchophylline, (+/-)-isorhynchophylline, (+/-)-mitraphylline, (+/-)-formosanine, (+/-)-isomitraphylline, and (+/-)-isoformosanine, is completed in a protecting-group free manner. Besides multigram-scaled operations, the notable feature of the synthesis is the application of two one-pot, sequential transformations. Namely, two key tetracyclic intermediates pyridinium salt 9 and monoester 14 were prepared by a one-pot N-alkylation/cross-dehydrogenative coupling sequence and a one-pot Michael/Karpocho sequence with minimal purification, respectively.
DOI10.1039/c6ra12766e
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000379493900004
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/28465
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Xu, Jun,Shao, Li-Dong,Shi, Xin,et al. Collective formal synthesis of (+/-)-rhynchophylline and homologues[J]. RSC ADVANCES,2016,6(68):63131-63135.
APA Xu, Jun,Shao, Li-Dong,Shi, Xin,Ren, Jian,Xia, Chengfeng,&Zhao, Qin-Shi.(2016).Collective formal synthesis of (+/-)-rhynchophylline and homologues.RSC ADVANCES,6(68),63131-63135.
MLA Xu, Jun,et al."Collective formal synthesis of (+/-)-rhynchophylline and homologues".RSC ADVANCES 6.68(2016):63131-63135.
Files in This Item: Download All
File Name/Size DocType Version Access License
10.1039@c6ra12766e.p(933KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
10.1039@c6ra12766e.p(933KB) 开放获取--View Download
10.1039@c6ra12766e.p(933KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Xu, Jun]'s Articles
[Shao, Li-Dong]'s Articles
[Shi, Xin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Xu, Jun]'s Articles
[Shao, Li-Dong]'s Articles
[Shi, Xin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Xu, Jun]'s Articles
[Shao, Li-Dong]'s Articles
[Shi, Xin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 10.1039@c6ra12766e.pdf
Format: Adobe PDF
This file does not support browsing at this time
File name: 10.1039@c6ra12766e.pdf
Format: Adobe PDF
This file does not support browsing at this time
File name: 10.1039@c6ra12766e.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.