A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin

doi:10.1016/j.tetlet.2016.02.061

	A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin
	Yu, Zhiyin 1,2; Wang, Li 1; Yang, Jing1 ; Zhang, Fan 3; Sun, Yun 2; Yu, Mingming 1; Yan, Yijun 1; Ma, Ya-Tuan 1; Huang, Sheng-Xiong1
	2016-03-23
发表期刊	TETRAHEDRON LETTERS
卷号	57 期号:12 页码:1375-1378
摘要	A new hygrolidin-type macrolide (1), together with one known derivative, oxohygrolidin (2), were isolated from the culture of Streptomyces sp. KIB-H869. The structure of the new compound was elucidated by means of extensive spectroscopic analysis. Moreover, by the biogenesis ratiocination and NMR data comparison, halichomycin and 2 were confirmed to have the same structure, which corrects the structural misrepresentation of halichomycin. The antifungal activities of the two compounds were evaluated. Published by Elsevier Ltd.
关键词	Streptomyces Type 1 Pks Oxohygrolidin Halichomycin Structure Revision
DOI	10.1016/j.tetlet.2016.02.061
收录类别	SCI
语种	英语
WOS记录号	WOS:000371941900020
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/26020
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.XinJiang Med Univ, Coll Tradit Chinese Med, Urumqi 830011, Peoples R China 3.North Sichuan Med Univ, Sch Pharm, Nanchong 637007, Sichuan, Peoples R China
推荐引用方式 GB/T 7714	Yu, Zhiyin,Wang, Li,Yang, Jing,et al. A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin[J]. TETRAHEDRON LETTERS,2016,57(12):1375-1378.
APA	Yu, Zhiyin.,Wang, Li.,Yang, Jing.,Zhang, Fan.,Sun, Yun.,...&Huang, Sheng-Xiong.(2016).A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin.TETRAHEDRON LETTERS,57(12),1375-1378.
MLA	Yu, Zhiyin,et al."A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin".TETRAHEDRON LETTERS 57.12(2016):1375-1378.

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