| A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin | |
Yu, Zhiyin1,2; Wang, Li1; Yang, Jing1 ; Zhang, Fan3; Sun, Yun2; Yu, Mingming1; Yan, Yijun1; Ma, Ya-Tuan1; Huang, Sheng-Xiong1
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| 2016-03-23 | |
| Source Publication | TETRAHEDRON LETTERS
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| Volume | 57Issue:12Pages:1375-1378 |
| Abstract | A new hygrolidin-type macrolide (1), together with one known derivative, oxohygrolidin (2), were isolated from the culture of Streptomyces sp. KIB-H869. The structure of the new compound was elucidated by means of extensive spectroscopic analysis. Moreover, by the biogenesis ratiocination and NMR data comparison, halichomycin and 2 were confirmed to have the same structure, which corrects the structural misrepresentation of halichomycin. The antifungal activities of the two compounds were evaluated. Published by Elsevier Ltd. |
| Keyword | Streptomyces Type 1 Pks Oxohygrolidin Halichomycin Structure Revision |
| DOI | 10.1016/j.tetlet.2016.02.061 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000371941900020 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/26020 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.XinJiang Med Univ, Coll Tradit Chinese Med, Urumqi 830011, Peoples R China 3.North Sichuan Med Univ, Sch Pharm, Nanchong 637007, Sichuan, Peoples R China |
| Recommended Citation GB/T 7714 | Yu, Zhiyin,Wang, Li,Yang, Jing,et al. A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin[J]. TETRAHEDRON LETTERS,2016,57(12):1375-1378. |
| APA | Yu, Zhiyin.,Wang, Li.,Yang, Jing.,Zhang, Fan.,Sun, Yun.,...&Huang, Sheng-Xiong.(2016).A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin.TETRAHEDRON LETTERS,57(12),1375-1378. |
| MLA | Yu, Zhiyin,et al."A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin".TETRAHEDRON LETTERS 57.12(2016):1375-1378. |
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| yu2016.pdf（481KB） | 开放获取 | CC BY-NC-SA | View Application Full Text | |||
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