Cytotoxic indole alkaloids from Tabemaemontana officinalis

doi:10.1016/j.phytochem.2014.12.025

	Cytotoxic indole alkaloids from Tabemaemontana officinalis
	Zhang, Bing-Jie; Teng, Xi-Feng; Bao, Mei-Fen; Zhong, Xiu-Hong; Ni, Ling; Cai, Xiang-Hai
	2015-12-01
发表期刊	PHYTOCHEMISTRY
卷号	120 页码:46-52
摘要	Continued interest in cytotoxic alkaloids resulted in the isolation of 37 alkaloids including 29 known monoterpenoid indole alkaloids from the aerial parts of Tabernaemontana officinalis. Of the remaining 8 alkaloids, six were bisindole alkaloids named taberdivarines A-F (1-6) and the two were monomers named taberdivarines G and H (7-8). Alkaloids 1 and 2 are voaphylline-vobasinyl type bisindole alkaloids, a structural type previously unknown, while 3-6 exhibited cytotoxicity against three human cancer cell lines HeLa, MCF-7, and SW480 with IC50 values ranging from 1.42 to 11.35 mu M. (C) 2014 Elsevier Ltd. All rights reserved.
关键词	Tabernaemontana Officinalis Apocynaceae Monoterpenoid Indole Alkaloid Bisindole Alkaloid Cytotoxicity
DOI	10.1016/j.phytochem.2014.12.025
收录类别	SCI
语种	英语
WOS记录号	WOS:000366962700005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25344
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Zhang, Bing-Jie,Teng, Xi-Feng,Bao, Mei-Fen,et al. Cytotoxic indole alkaloids from Tabemaemontana officinalis[J]. PHYTOCHEMISTRY,2015,120:46-52.
APA	Zhang, Bing-Jie,Teng, Xi-Feng,Bao, Mei-Fen,Zhong, Xiu-Hong,Ni, Ling,&Cai, Xiang-Hai.(2015).Cytotoxic indole alkaloids from Tabemaemontana officinalis.PHYTOCHEMISTRY,120,46-52.
MLA	Zhang, Bing-Jie,et al."Cytotoxic indole alkaloids from Tabemaemontana officinalis".PHYTOCHEMISTRY 120(2015):46-52.

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