Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis

doi:10.1016/j.phytochem.2015.10.008

	Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis
	Qin,Xu-Jie; Yu,Mu-Yuan; Ni,Wei; Yan,Huan; Chen,Chang-Xiang; Cheng,Yung-Chi; He,Li; Liu,Hai-Yang
	2016
发表期刊	PHYTOCHEMISTRY
卷号	121 页码:20-29
摘要	Phytochemical investigation of the stems and leaves of Paris polyphyila var. yunnanensis led to isolation of 12 steroidal saponins, chonglouosides SL-9-SL-20, which had not been described previously, along with 13 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Four of the twelve steroidal saponins possessed three steroidal aglycones which have not been reported in nature. Steroidal saponins were also evaluated for their cytotoxicities against two human cancer cell lines (HepG2 and HEK293) and anti-HCV effects. One known steroidal saponin was the most cytotoxic compound overall with IC50 values of 2.9 +/- 0.5 mu M and 5.0 +/- 0.6 mu M against HepG2 and HEK293 cell lines, respectively, while none showed anti-HCV activity at a concentration of 20 mu M. (C) 2015 Elsevier Ltd. All rights reserved.
关键词	Paris Polyphylla Var. Yunnanensis Trilliaceae Steroidal Saponins Chonglouosides Sl-9-sl-20 Cytotoxicity Anti-hcv Activity
DOI	10.1016/j.phytochem.2015.10.008
收录类别	SCI
语种	英语
WOS记录号	WOS:000366445300003
引用统计	被引频次：65[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25262
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Qin,Xu-Jie,Yu,Mu-Yuan,Ni,Wei,et al. Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis[J]. PHYTOCHEMISTRY,2016,121:20-29.
APA	Qin,Xu-Jie.,Yu,Mu-Yuan.,Ni,Wei.,Yan,Huan.,Chen,Chang-Xiang.,...&Liu,Hai-Yang.(2016).Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis.PHYTOCHEMISTRY,121,20-29.
MLA	Qin,Xu-Jie,et al."Steroidal saponins from stems and leaves of Paris polyphylla var. yunnanensis".PHYTOCHEMISTRY 121(2016):20-29.

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