| Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense | |
| He, Ya-Cong1,2; Peng, Cheng1,2; Xie, Xiao-Fang1,2; Chen, Ming-Hua3,4; Li, Xiao-Nian5; Li, Meng-Ting1,2; Zhou, Qin-Mei1,2; Guo, Li1,2; Xiong, Liang1,2 | |
| 2015 | |
| 发表期刊 | RSC ADVANCES
 |
| 卷号 | 5期号:94页码:76788-76794 |
| 摘要 | Penchinones A-D (1-4), two pairs of novel cis-trans lignan isomers with rearranged neolignane carbon skeletons, together with six known flavonoids (5-10), were isolated from the ethyl acetate-soluble portion of a hepatoprotective water decoction of Penthorum chinense. Their structures were determined by extensive spectroscopic data analysis, ECD calculation, and single-crystal X-ray diffraction. Penchinones C and D (3 and 4) featured an unprecedented 7,30-neolignane carbon skeleton. Penchinone A (1) exhibited protective activity against acetaminophen-induced damage to the HL7702 hepatocyte and selective cytotoxicity against the human cancer ovarian cell line, Hey, in vitro. |
| DOI | 10.1039/c5ra15982b |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361559700018 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/25151 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chengdu Univ Tradit Chinese Med, State Key Lab Breeding Base Systemat Res Dev & Ut, Chengdu 611137, Peoples R China 2.Chengdu Univ Tradit Chinese Med, Sch Pharm, Chengdu 611137, Peoples R China 3.Chinese Acad Med Sci, Inst Med Biotechnol, Beijing 100050, Peoples R China 4.Peking Union Med Coll, Beijing 100050, Peoples R China 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Ya-Cong,Peng, Cheng,Xie, Xiao-Fang,et al. Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense[J]. RSC ADVANCES,2015,5(94):76788-76794. |
| APA | He, Ya-Cong.,Peng, Cheng.,Xie, Xiao-Fang.,Chen, Ming-Hua.,Li, Xiao-Nian.,...&Xiong, Liang.(2015).Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense.RSC ADVANCES,5(94),76788-76794. |
| MLA | He, Ya-Cong,et al."Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense".RSC ADVANCES 5.94(2015):76788-76794. |
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| he2015.pdf（1675KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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