Structurally diversified diterpenoids from Euphorbia dracunculoides | |
Wang, Li; Ma, Ya-Tuan; Sun, Qian-Yun; Li, Xiao-Nian; Yan, Yijun; Yang, Jing; Yang, Fu-Mei; Liu, Feng-Yi; Zang, Zhen; Wu, Xiang-Hua; Huang, Sheng-Xiong; Zhao, Yong | |
2015-08-26 | |
发表期刊 | TETRAHEDRON |
卷号 | 71期号:34页码:5484-5493 |
摘要 | Extensive phytochemical investigation of the aerial parts of Euphorbia dracunculoides led to the isolation of 19 structurally diversified diterpenoids with five different carbon skeletons, including six new lathyrane glycosides (1-6), three new cyclomyrsinanes (7-9), three new premyrsinanes (10-12), and one new 10,18-dihydromyrsinane (13). Their structures were elucidated by means of extensive spectroscopic analysis, and the structure of 7 was further confirmed by X-ray crystallography. Compounds 1-6 are the first examples of C-17-glycosylated lathyrane diterpenoids. Selected isolates were evaluated for their cytotoxicity against five cancer cell lines. Only the tiglianes exhibited moderate activity. (C) 2015 Elsevier Ltd. All rights reserved. |
关键词 | Euphorbia Dracunculoides Diterpenoid Lathyrane Glycoside Myrsinane Tigliane |
DOI | 10.1016/j.tet.2015.06.078 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000359033700007 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/25084 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
推荐引用方式 GB/T 7714 | Wang, Li,Ma, Ya-Tuan,Sun, Qian-Yun,et al. Structurally diversified diterpenoids from Euphorbia dracunculoides[J]. TETRAHEDRON,2015,71(34):5484-5493. |
APA | Wang, Li.,Ma, Ya-Tuan.,Sun, Qian-Yun.,Li, Xiao-Nian.,Yan, Yijun.,...&Zhao, Yong.(2015).Structurally diversified diterpenoids from Euphorbia dracunculoides.TETRAHEDRON,71(34),5484-5493. |
MLA | Wang, Li,et al."Structurally diversified diterpenoids from Euphorbia dracunculoides".TETRAHEDRON 71.34(2015):5484-5493. |
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