Structurally diversified diterpenoids from Euphorbia dracunculoides
Wang, Li; Ma, Ya-Tuan; Sun, Qian-Yun; Li, Xiao-Nian; Yan, Yijun; Yang, Jing; Yang, Fu-Mei; Liu, Feng-Yi; Zang, Zhen; Wu, Xiang-Hua; Huang, Sheng-Xiong; Zhao, Yong
2015-08-26
发表期刊TETRAHEDRON
卷号71期号:34页码:5484-5493
摘要Extensive phytochemical investigation of the aerial parts of Euphorbia dracunculoides led to the isolation of 19 structurally diversified diterpenoids with five different carbon skeletons, including six new lathyrane glycosides (1-6), three new cyclomyrsinanes (7-9), three new premyrsinanes (10-12), and one new 10,18-dihydromyrsinane (13). Their structures were elucidated by means of extensive spectroscopic analysis, and the structure of 7 was further confirmed by X-ray crystallography. Compounds 1-6 are the first examples of C-17-glycosylated lathyrane diterpenoids. Selected isolates were evaluated for their cytotoxicity against five cancer cell lines. Only the tiglianes exhibited moderate activity. (C) 2015 Elsevier Ltd. All rights reserved.
关键词Euphorbia Dracunculoides Diterpenoid Lathyrane Glycoside Myrsinane Tigliane
DOI10.1016/j.tet.2015.06.078
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000359033700007
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被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/25084
专题植物化学与西部植物资源持续利用国家重点实验室
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Wang, Li,Ma, Ya-Tuan,Sun, Qian-Yun,et al. Structurally diversified diterpenoids from Euphorbia dracunculoides[J]. TETRAHEDRON,2015,71(34):5484-5493.
APA Wang, Li.,Ma, Ya-Tuan.,Sun, Qian-Yun.,Li, Xiao-Nian.,Yan, Yijun.,...&Zhao, Yong.(2015).Structurally diversified diterpenoids from Euphorbia dracunculoides.TETRAHEDRON,71(34),5484-5493.
MLA Wang, Li,et al."Structurally diversified diterpenoids from Euphorbia dracunculoides".TETRAHEDRON 71.34(2015):5484-5493.
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