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题名: Structurally diversified diterpenoids from Euphorbia dracunculoides
作者: Wang, Li; Ma, Ya-Tuan; Sun, Qian-Yun; Li, Xiao-Nian; Yan, Yijun; Yang, Jing; Yang, Fu-Mei; Liu, Feng-Yi; Zang, Zhen; Wu, Xiang-Hua; null(黄胜雄); Zhao, Yong
刊名: TETRAHEDRON
关键词: Euphorbia dracunculoides ; Diterpenoid ; Lathyrane glycoside ; Myrsinane ; Tigliane
英文摘要: Extensive phytochemical investigation of the aerial parts of Euphorbia dracunculoides led to the isolation of 19 structurally diversified diterpenoids with five different carbon skeletons, including six new lathyrane glycosides (1-6), three new cyclomyrsinanes (7-9), three new premyrsinanes (10-12), and one new 10,18-dihydromyrsinane (13). Their structures were elucidated by means of extensive spectroscopic analysis, and the structure of 7 was further confirmed by X-ray crystallography. Compounds 1-6 are the first examples of C-17-glycosylated lathyrane diterpenoids. Selected isolates were evaluated for their cytotoxicity against five cancer cell lines. Only the tiglianes exhibited moderate activity. (C) 2015 Elsevier Ltd. All rights reserved.
出版日期: 2015-08-26
卷号: 71, 期号:34, 页码:5484-5493
DOI标识: 10.1016/j.tet.2015.06.078
语种: 英语
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/25084
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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