Antimicrobially Active Isoquinoline Alkaloids from Litsea cubeba

doi:10.1055/s-0028-1088344

	Antimicrobially Active Isoquinoline Alkaloids from Litsea cubeba
	Feng, Tao 1,2; Xu, Yan 3; Cai, Xiang-Hai1 ; Du, Zhi-Zhi1 ; Luo, Xiao-Dong1
	2009
发表期刊	PLANTA MEDICA
卷号	75 期号:1 页码:76-79
摘要	Bioassay-guided fractionation of the alkaloidal extract of the aerial part of Litsea cubeba led to the isolation of two new isoquinoline alkaloids, (+)-N-(methoxycarbonyl)-N-norboldine (1) and (+)-isoboldine beta-N-oxide (2), together with 11 known analogues (3-13). Their structures were established by extensive spectroscopic techniques and by comparing spectroscopic data with those in the literature. Compounds 1 and 4 showed antimicrobial activities. This is the first report on the presence of compounds 1, 2, 6, 8, 9, 11, and 12 in this plant and on the antimicrobial activities of 1 and 4. The bioactivities of isoquinoline alkaloids are also at least partly responsible for the pharmacological function of the folk medicinal plant Litsea cubeba.
关键词	Litsea Cubeba Lauraceae Isoquinoline Alkaloids Antimicrobial Activity (+)-n-(Methoxycarbony)-n-norboldine (+)-isoboldine Beta-n-oxide
DOI	10.1055/s-0028-1088344
收录类别	SCI
语种	英语
WOS记录号	WOS:000263032200015
引用统计	被引频次：31[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/23890
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 3.Yangzhou Univ, Coll Biosci & Biotechnol, Yangzhou, Peoples R China
推荐引用方式 GB/T 7714	Feng, Tao,Xu, Yan,Cai, Xiang-Hai,et al. Antimicrobially Active Isoquinoline Alkaloids from Litsea cubeba[J]. PLANTA MEDICA,2009,75(1):76-79.
APA	Feng, Tao,Xu, Yan,Cai, Xiang-Hai,Du, Zhi-Zhi,&Luo, Xiao-Dong.(2009).Antimicrobially Active Isoquinoline Alkaloids from Litsea cubeba.PLANTA MEDICA,75(1),76-79.
MLA	Feng, Tao,et al."Antimicrobially Active Isoquinoline Alkaloids from Litsea cubeba".PLANTA MEDICA 75.1(2009):76-79.

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