A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters
Gui, Yong-Yuan1,2; Yang, Jian1,2; Qi, Liang-Wen1,2; Wang, Xiao1,2; Tian, Fang1; Li, Xiao-Nian3; Peng, Lin1; Wang, Li-Xin1; Peng,L (reprint author),Chinese Acad Sci,Chengdu Inst Organ Chem,Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro,Chengdu 610041,Peoples R China.
2015
发表期刊ORGANIC & BIOMOLECULAR CHEMISTRY
卷号13期号:22页码:6371-6379
摘要A cinchona alkaloid catalyzed diastereoselective and enantioselective sulfa-Michael/aldol cascade reaction between 1,4-dithiane-2,5-diol and isoindigos has been successfully developed to afford the highly congested bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters in high yields (up to 91%), excellent diastereoselectivities (up to >20 : 1 dr), and good enantioselectivities (up to 98% ee). Some synthetic transformations of the reaction products were also studied.
资助信息National Natural Science Foundation of China [21272230]
学科领域Chemistry, Organic
DOI10.1039/c5ob00774g
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000355489600028
引用统计
被引频次:28[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/21353
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Peng,L (reprint author),Chinese Acad Sci,Chengdu Inst Organ Chem,Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro,Chengdu 610041,Peoples R China.
作者单位1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu 610041, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Peoples R China
推荐引用方式
GB/T 7714
Gui, Yong-Yuan,Yang, Jian,Qi, Liang-Wen,et al. A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2015,13(22):6371-6379.
APA Gui, Yong-Yuan.,Yang, Jian.,Qi, Liang-Wen.,Wang, Xiao.,Tian, Fang.,...&Peng,L .(2015).A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters.ORGANIC & BIOMOLECULAR CHEMISTRY,13(22),6371-6379.
MLA Gui, Yong-Yuan,et al."A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters".ORGANIC & BIOMOLECULAR CHEMISTRY 13.22(2015):6371-6379.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
gui2015.pdf(407KB)期刊论文出版稿开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Gui, Yong-Yuan]的文章
[Yang, Jian]的文章
[Qi, Liang-Wen]的文章
百度学术
百度学术中相似的文章
[Gui, Yong-Yuan]的文章
[Yang, Jian]的文章
[Qi, Liang-Wen]的文章
必应学术
必应学术中相似的文章
[Gui, Yong-Yuan]的文章
[Yang, Jian]的文章
[Qi, Liang-Wen]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。