| New antimicrobial pregnane glycosides from the stem of Ecdysanthera rosea | |
Song, Chang-Wei1,2; Lunga, Paul-Keilah1,3; Qin, Xu-Jie1,2 ; Cheng, Gui-Guang1,2; Gu, Jian-Long1,2; Liu, Ya-Ping1; Luo, Xiao-Dong1
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| 2014-12-01 | |
| 发表期刊 | FITOTERAPIA
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| 卷号 | 99页码:267-275 |
| 摘要 | Phytochemical investigation on the stem of Ecdysanthera rosea led to the isolation of eight new C-21 pregnane glycoside ecdysosides A-H (1-8), together with one known pregnane glycoside ecdysantheroside A (9). Their structures were elucidated based on extensive spectroscopic data (MS, IR, 1D and 2D NMR) analysis, as well as comparison with the reported literature data. Antimicrobial activities of all the compounds were evaluated against bacteria and yeasts. Compounds 1, 9, 3 and 5 exhibited moderate antibacterial activities against respective Enterococcus faecalis and Providensia smartii, with MIC value of 12.5 mu g/mL. Compound 8 showed significant anti-yeast activity against Cryptococcus neoformans with MIC value of 12.5 mu g/mL. (C) 2014 Elsevier B.V. All rights reserved. |
| 关键词 | Ecdysanthera Rosea Apocynaceae Pregnane Glycosides Antimicrobial Activity |
| DOI | 10.1016/j.fitote.2014.10.008 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347019000034 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/20474 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Yaounde I, Fac Sci, Dept Biochem, Lab Phytobiochem & Med Plants Study, Yaounde, Cameroon |
| 推荐引用方式 GB/T 7714 | Song, Chang-Wei,Lunga, Paul-Keilah,Qin, Xu-Jie,et al. New antimicrobial pregnane glycosides from the stem of Ecdysanthera rosea[J]. FITOTERAPIA,2014,99:267-275. |
| APA | Song, Chang-Wei.,Lunga, Paul-Keilah.,Qin, Xu-Jie.,Cheng, Gui-Guang.,Gu, Jian-Long.,...&Luo, Xiao-Dong.(2014).New antimicrobial pregnane glycosides from the stem of Ecdysanthera rosea.FITOTERAPIA,99,267-275. |
| MLA | Song, Chang-Wei,et al."New antimicrobial pregnane glycosides from the stem of Ecdysanthera rosea".FITOTERAPIA 99(2014):267-275. |
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