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题名: Salviprzols A and B, C-21- and C-22-terpenoids from the roots of Salvia przewalskii Maxim
作者: Xue, Yongbo1; Wu, Ye1; Zhu, Hucheng1; Li, Xiao-Nian2; Qian, Jin-Fu3; Lai, Yongji4; Chen, Chunmei1; Yao, Guangmin1; Luo, Zengwei1; null(李艳)2; Zhang, Yonghui1
刊名: FITOTERAPIA
出版日期: 2014-12-01
卷号: 99, 页码:204-210
关键词: Labiatae ; Salvia przewalskii ; C-23-terpenoids ; Salviprzols ; X-ray diffraction
DOI: 10.1016/j.fitote.2014.09.022
文章类型: Article
英文摘要: Two C-21- and C-22-terpenoids, salviprzols A (1) and B (2), together with 24 known compounds including 17 diterpenoids (3-19), a triterpenoid (20), and 6 phenolic derivatives (21-26), were isolated from the roots of Salvia przewalskii Maxim. Salviprzols A and B represented a new subtype of C-23-terpenoids featured by an additional 2-oxopropyl moiety at C-12 and a rare gamma-hydroxyl-alpha-methyl-alpha,beta-unsaturated-gamma-lactone ring system. Their structures were elucidated by extensive spectroscopic analyses, and the structure of 2 was confirmed by a single-crystal X-ray diffraction crystallography. The cytotoxic activities of the new isolates were tested. A plausible biosynthetic pathway for 1 and 2 was also proposed. (C) 2014 Elsevier B.V. All rights reserved.
类目[WOS]: Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: ABIETANE DITERPENOIDS ; MILTIORRHIZA ; TANSHINONES ; SKELETON ; DANSHEN ; DERIVATIVES ; ACID
收录类别: SCI
语种: 英语
WOS记录号: WOS:000347019000026
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20425
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Wuhan 430030, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resourcese West C, Kunming 650204, Peoples R China
3.Dali Univ, Sch Pharm, Dali 671003, Peoples R China
4.Huazhong Univ Sci & Technol, Tongji Med Coll, Cent Hosp Wuhan, Wuhan 430000, Peoples R China
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