中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Construction of Tetracyclic 3-Spirooxindole through Cross-Dehydrogenation of Pyridinium: Applications in Facile Synthesis of (+/-)-Corynoxine and (+/-)-Corynoxine B
作者: Xu, Jun1, 2; Shao, Li-Dong1; Li, Dashan1, 2; Deng, Xu1; Liu, Yu-Chen1, 2; null(赵勤实)1; null(夏成峰)1
刊名: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
出版日期: 2014-12-31
卷号: 136, 期号:52, 页码:17962-17965
DOI: 10.1021/ja5121343
文章类型: Article
英文摘要: A facile and straightforward method was developed to construct the fused tetracyclic 3-spirooxindole skeleton, which exists widely in natural products. The formation of the tetracyclic 3-spirooxindole structure was achieved through a transition-metal-free intramolecular cross-dehydrogenative coupling of pyridinium, which were formed in situ by the condensation of 3-(2-bromoethyl)indolin-2-one derivatives with 3-substituted pyridines. As examples of the application of this new methodology, two potentially medicinal natural products, (+/-)-corynoxine and (+/-)-corynoxine B, were efficiently synthesized in five scalable steps.
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: ENANTIOSELECTIVE FORMAL SYNTHESIS ; 1ST TOTAL-SYNTHESIS ; OXINDOLE ALKALOIDS ; INDOLE ALKALOIDS ; RING-EXPANSION ; GENERAL-APPROACH ; ALPHA-SYNUCLEIN ; ISORHYNCHOPHYLLINE ; RHYNCHOPHYLLINE ; RHYNCOPHYLLINE
收录类别: SCI ; IC ; CCR
语种: 英语
WOS记录号: WOS:000347438300018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20421
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
ja5121343.pdf(696KB)----开放获取View 联系获取全文

作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Xu, Jun]'s Articles
[Shao, Li-Dong]'s Articles
[Li, Dashan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Xu, Jun]‘s Articles
[Shao, Li-Dong]‘s Articles
[Li, Dashan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: ja5121343.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace