Unraveling the Metabolic Pathway in Leucosceptrum canum by Isolation of New Defensive Leucosceptroid Degradation Products and Biomimetic Model Synthesis

doi:10.1021/ol503230s

	Unraveling the Metabolic Pathway in Leucosceptrum canum by Isolation of New Defensive Leucosceptroid Degradation Products and Biomimetic Model Synthesis
	Luo, Shi-Hong 1; Hugelshofer, Cedric L.2; Hua, Juan 1,3; Jing, Shu-Xi 1,3; Li, Chun-Huan 1; Liu, Yan 1; Li, Xiao-Nian 1; Zhao, Xu 1; Magauer, Thomas 2; Li, Sheng-Hong1
	2014-12-19
发表期刊	ORGANIC LETTERS
卷号	16 期号:24 页码:6416-6419
摘要	Seven new leucosceptroid degradation products possessing a C-20, C-21, or C-25 framework, norleucosceptroids DH (1-5), leucosceptroids P (6), and Q (7), have been isolated from Leucosceptrum canum. Their structures were determined by comprehensive NMR, MS, and single-crystal X-ray diffraction analyses. Discovery of these key intermediates, together with the biomimetic oxidation of a model system, supports the hypothesis that two biosynthetic pathways are operative. Antifeedant activity was observed for compounds 1-3.
DOI	10.1021/ol503230s
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000346759900039
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/20418
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Munich, Dept Chem & Pharm, D-81377 Munich, Germany 3.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Luo, Shi-Hong,Hugelshofer, Cedric L.,Hua, Juan,et al. Unraveling the Metabolic Pathway in Leucosceptrum canum by Isolation of New Defensive Leucosceptroid Degradation Products and Biomimetic Model Synthesis[J]. ORGANIC LETTERS,2014,16(24):6416-6419.
APA	Luo, Shi-Hong.,Hugelshofer, Cedric L..,Hua, Juan.,Jing, Shu-Xi.,Li, Chun-Huan.,...&Li, Sheng-Hong.(2014).Unraveling the Metabolic Pathway in Leucosceptrum canum by Isolation of New Defensive Leucosceptroid Degradation Products and Biomimetic Model Synthesis.ORGANIC LETTERS,16(24),6416-6419.
MLA	Luo, Shi-Hong,et al."Unraveling the Metabolic Pathway in Leucosceptrum canum by Isolation of New Defensive Leucosceptroid Degradation Products and Biomimetic Model Synthesis".ORGANIC LETTERS 16.24(2014):6416-6419.

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