| Steroidal saponins with induced platelet aggregation activity from the aerial parts of Paris verticillata | |
Sun, Chang-Li1,2; Ni, Wei1; Yan, Huan1; Liu, Zhen-Hua1; Yang, Lian1; Si, Yong-Ai1 ; Hua, Yan2; Chen, Chang-Xiang1; He, Li3; Zhao, Jin-Hua1; Liu, Hai-Yang1
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| 2014-12-15 | |
| 发表期刊 | STEROIDS
 |
| 卷号 | 92页码:90-95 |
| 摘要 | In order to utilize and protect the resources of Rhizoma Paridis rationally, we carried out a phytochemical investigation on the non-medicinal (aerial) parts of Paris verticillata that led to the isolation of fifteen steroidal saponins. Among them, three are new spirostanol saponins, named parisverticosides A-C (1-3), as well as one new cholestane glycoside, named parisverticoside D (4). Their structures were elucidated by extensive spectroscopic analysis and acid hydrolysis. The aglycone of compound 1 is a new spirostane and identified as (23S,24S,25S)-spirost-5-en-1 beta,3 beta,23, 24-tetraol. The selected isolates were evaluated for induced platelet aggregation activity and compound 5 showed 62% maximal platelet aggregation rate at the concentration of 300 mu g/mL. (C) 2014 Elsevier Inc. All rights reserved. |
| 关键词 | Paris Verticillata Liliaceae Steroidal Saponins Parisverticosides A-d Induced Platelet Aggregation Activity |
| DOI | 10.1016/j.steroids.2014.09.008 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347134300013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/20412 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Southwest Forestry Univ, Coll Forestry, Kunming 650224, Peoples R China 3.Kunming Med Univ, Affiliated Hosp 1, Dept Dermatol, Kunming 650032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Chang-Li,Ni, Wei,Yan, Huan,et al. Steroidal saponins with induced platelet aggregation activity from the aerial parts of Paris verticillata[J]. STEROIDS,2014,92:90-95. |
| APA | Sun, Chang-Li.,Ni, Wei.,Yan, Huan.,Liu, Zhen-Hua.,Yang, Lian.,...&Liu, Hai-Yang.(2014).Steroidal saponins with induced platelet aggregation activity from the aerial parts of Paris verticillata.STEROIDS,92,90-95. |
| MLA | Sun, Chang-Li,et al."Steroidal saponins with induced platelet aggregation activity from the aerial parts of Paris verticillata".STEROIDS 92(2014):90-95. |
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