Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica

doi:10.1021/ol701540y

	Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica
	Liu, Ji-Feng ; Jiang, Zhi-Yong ; Wang, Rui-Rui ; Zheng, Yong-Tang ; Chen, Ji-Jun; Zhang, Xue-Mei; Ma, Yun-Bao
	2007-10-11
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	9 期号:21 页码:4127-4129
摘要	9 alpha,13 alpha-Dihydroxylisopropylidenylisatisine A (1), which was derived from isatisine A (2) and possessed an unprecedented fused pentacyclic skeleton, was isolated from the leaves of Isatis indigotica Fort. The structure and relative configuration were elucidated on the basis of extensive NMR analyses and finally determined by single-crystal X-ray diffraction. Compound 1 showed moderate anti-HIV-1 activity with EC50 = 37.8 mu M and S1 = 7.98.
关键词	Cells
学科领域	Chemistry ; Organic
DOI	10.1021/ol701540y
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000249987200011
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/2013
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Lab Mol Immunopharmacol, Kunming 650223, Peoples R China 3.Chinese Acad Sci, Grad Sch, Joint Lab Anti Viral Nat Med, Kunming Branch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Liu, Ji-Feng,Jiang, Zhi-Yong,Wang, Rui-Rui,et al. Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica[J]. ORGANIC LETTERS,2007,9(21):4127-4129.
APA	Liu, Ji-Feng.,Jiang, Zhi-Yong.,Wang, Rui-Rui.,Zheng, Yong-Tang.,Chen, Ji-Jun.,...&Ma, Yun-Bao.(2007).Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica.ORGANIC LETTERS,9(21),4127-4129.
MLA	Liu, Ji-Feng,et al."Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica".ORGANIC LETTERS 9.21(2007):4127-4129.

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