Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica
Liu, Ji-Feng; Jiang, Zhi-Yong; Wang, Rui-Rui; Zheng, Yong-Tang; Chen, Ji-Jun; Zhang, Xue-Mei; Ma, Yun-Bao
2007-10-11
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号9期号:21页码:4127-4129
摘要9 alpha,13 alpha-Dihydroxylisopropylidenylisatisine A (1), which was derived from isatisine A (2) and possessed an unprecedented fused pentacyclic skeleton, was isolated from the leaves of Isatis indigotica Fort. The structure and relative configuration were elucidated on the basis of extensive NMR analyses and finally determined by single-crystal X-ray diffraction. Compound 1 showed moderate anti-HIV-1 activity with EC50 = 37.8 mu M and S1 = 7.98.
关键词Cells
学科领域Chemistry ; Organic
DOI10.1021/ol701540y
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000249987200011
引用统计
被引频次:94[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2013
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Lab Mol Immunopharmacol, Kunming 650223, Peoples R China
3.Chinese Acad Sci, Grad Sch, Joint Lab Anti Viral Nat Med, Kunming Branch, Beijing 100039, Peoples R China
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Liu, Ji-Feng,Jiang, Zhi-Yong,Wang, Rui-Rui,et al. Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica[J]. ORGANIC LETTERS,2007,9(21):4127-4129.
APA Liu, Ji-Feng.,Jiang, Zhi-Yong.,Wang, Rui-Rui.,Zheng, Yong-Tang.,Chen, Ji-Jun.,...&Ma, Yun-Bao.(2007).Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica.ORGANIC LETTERS,9(21),4127-4129.
MLA Liu, Ji-Feng,et al."Isatisine a, a novel alkaloid with an unprecedented skeleton from leaves of isatis indigotica".ORGANIC LETTERS 9.21(2007):4127-4129.
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