Antibacterial lignans and triterpenoids from Rostellularia procumbens

doi:10.1055/s-2007-993747

	Antibacterial lignans and triterpenoids from Rostellularia procumbens
	Yongli Zhang; Fukai Bao; Juanjuan Hu; Shengwang Liang; YuZhang; Guanhua Du; CaijunZhang; Yongxian Cheng
	2007-12-01
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	73 期号:15 页码:1596-1599
摘要	One new lignan, rostellulin A (1), four known lignans, justin B (2), justicidin C (3), cilinaphthalide A (4), and justicidin A (5), and four known triterpenoids, ursolic acid (6), euscaphic acid (7), 2 alpha-hydroxyursolic acid (8), and tormentic acid (9), have been isolated from the whole plants of Rostellularia procumbens. Their structures were established on the basis of spectral data, including extensive NMR experiments. To our knowledge, compounds 6-9 are known compounds but not previously isolated from R. procumbens, 4 was previously reported from other Rostellularia species. Antibacterial activities of 1-9 were evaluated against eight bacterial strains with the agar dilution method, and they were found to possess antimicrobial activity with MIC values in the range of 1.56-100 mu g/mL. None of the lignans exhibited cytotoxic activity against HCT-8 and Bel-7402 cells at concentrations up to 5 pg/mL.
关键词	Necrosis-factor-alpha Justicia-procumbens Arylnaphthalide Lignans Cytotoxic Lignans Macrophages Apoptosis Cells
学科领域	Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI	10.1055/s-2007-993747
收录类别	SCI
语种	英语
WOS记录号	WOS:000252715400014
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/1965
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Yongli Zhang,Fukai Bao,Juanjuan Hu,et al. Antibacterial lignans and triterpenoids from Rostellularia procumbens[J]. PLANTA MEDICA,2007,73(15):1596-1599.
APA	Yongli Zhang.,Fukai Bao.,Juanjuan Hu.,Shengwang Liang.,YuZhang.,...&Yongxian Cheng.(2007).Antibacterial lignans and triterpenoids from Rostellularia procumbens.PLANTA MEDICA,73(15),1596-1599.
MLA	Yongli Zhang,et al."Antibacterial lignans and triterpenoids from Rostellularia procumbens".PLANTA MEDICA 73.15(2007):1596-1599.

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