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题名: Antibacterial lignans and triterpenoids from Rostellularia procumbens
作者: Yongli Zhang; Fukai Bao; Juanjuan Hu; Shengwang Liang; YuZhang; Guanhua Du; CaijunZhang; Yongxian Cheng
刊名: PLANTA MEDICA
关键词: NECROSIS-FACTOR-ALPHA ; JUSTICIA-PROCUMBENS ; ARYLNAPHTHALIDE LIGNANS ; CYTOTOXIC LIGNANS ; MACROPHAGES ; APOPTOSIS ; CELLS
英文摘要: One new lignan, rostellulin A (1), four known lignans, justin B (2), justicidin C (3), cilinaphthalide A (4), and justicidin A (5), and four known triterpenoids, ursolic acid (6), euscaphic acid (7), 2 alpha-hydroxyursolic acid (8), and tormentic acid (9), have been isolated from the whole plants of Rostellularia procumbens. Their structures were established on the basis of spectral data, including extensive NMR experiments. To our knowledge, compounds 6-9 are known compounds but not previously isolated from R. procumbens, 4 was previously reported from other Rostellularia species. Antibacterial activities of 1-9 were evaluated against eight bacterial strains with the agar dilution method, and they were found to possess antimicrobial activity with MIC values in the range of 1.56-100 mu g/mL. None of the lignans exhibited cytotoxic activity against HCT-8 and Bel-7402 cells at concentrations up to 5 pg/mL.
出版日期: 2007-12-01
卷号: 73, 期号:15, 页码:1596-1599
语种: 英语
收录类别: SCI
学科分类: Plant Sciences; Chemistry; Medicinal; Pharmacology & Pharmacy
ISSN号: 0032-0943
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/1965
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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Recommended Citation:
Zhang, YL; Bao, FK; Hu, JJ; Liang, SW; Zhang, Y; Du, GH; Zhang, CJ; Cheng, YX.Antibacterial lignans and triterpenoids from Rostellularia procumbens,PLANTA MEDICA,2007,73(15):1596-1599
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文件名: planta medica 2007-73-15-1596-1599.pdf
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