| Antibacterial lignans and triterpenoids from Rostellularia procumbens | |
| Yongli Zhang; Fukai Bao; Juanjuan Hu; Shengwang Liang; YuZhang; Guanhua Du; CaijunZhang; Yongxian Cheng | |
| 2007-12-01 | |
| 发表期刊 | PLANTA MEDICA
 |
| ISSN | 0032-0943 |
| 卷号 | 73期号:15页码:1596-1599 |
| 摘要 | One new lignan, rostellulin A (1), four known lignans, justin B (2), justicidin C (3), cilinaphthalide A (4), and justicidin A (5), and four known triterpenoids, ursolic acid (6), euscaphic acid (7), 2 alpha-hydroxyursolic acid (8), and tormentic acid (9), have been isolated from the whole plants of Rostellularia procumbens. Their structures were established on the basis of spectral data, including extensive NMR experiments. To our knowledge, compounds 6-9 are known compounds but not previously isolated from R. procumbens, 4 was previously reported from other Rostellularia species. Antibacterial activities of 1-9 were evaluated against eight bacterial strains with the agar dilution method, and they were found to possess antimicrobial activity with MIC values in the range of 1.56-100 mu g/mL. None of the lignans exhibited cytotoxic activity against HCT-8 and Bel-7402 cells at concentrations up to 5 pg/mL. |
| 关键词 | Necrosis-factor-alpha Justicia-procumbens Arylnaphthalide Lignans Cytotoxic Lignans Macrophages Apoptosis Cells |
| 学科领域 | Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1055/s-2007-993747 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000252715400014 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/1965 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Yongli Zhang,Fukai Bao,Juanjuan Hu,et al. Antibacterial lignans and triterpenoids from Rostellularia procumbens[J]. PLANTA MEDICA,2007,73(15):1596-1599. |
| APA | Yongli Zhang.,Fukai Bao.,Juanjuan Hu.,Shengwang Liang.,YuZhang.,...&Yongxian Cheng.(2007).Antibacterial lignans and triterpenoids from Rostellularia procumbens.PLANTA MEDICA,73(15),1596-1599. |
| MLA | Yongli Zhang,et al."Antibacterial lignans and triterpenoids from Rostellularia procumbens".PLANTA MEDICA 73.15(2007):1596-1599. |
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