Antibacterial lignans and triterpenoids from Rostellularia procumbens
Yongli Zhang; Fukai Bao; Juanjuan Hu; Shengwang Liang; YuZhang; Guanhua Du; CaijunZhang; Yongxian Cheng
2007-12-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号73期号:15页码:1596-1599
摘要One new lignan, rostellulin A (1), four known lignans, justin B (2), justicidin C (3), cilinaphthalide A (4), and justicidin A (5), and four known triterpenoids, ursolic acid (6), euscaphic acid (7), 2 alpha-hydroxyursolic acid (8), and tormentic acid (9), have been isolated from the whole plants of Rostellularia procumbens. Their structures were established on the basis of spectral data, including extensive NMR experiments. To our knowledge, compounds 6-9 are known compounds but not previously isolated from R. procumbens, 4 was previously reported from other Rostellularia species. Antibacterial activities of 1-9 were evaluated against eight bacterial strains with the agar dilution method, and they were found to possess antimicrobial activity with MIC values in the range of 1.56-100 mu g/mL. None of the lignans exhibited cytotoxic activity against HCT-8 and Bel-7402 cells at concentrations up to 5 pg/mL.
关键词Necrosis-factor-alpha Justicia-procumbens Arylnaphthalide Lignans Cytotoxic Lignans Macrophages Apoptosis Cells
学科领域Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-2007-993747
收录类别SCI
语种英语
WOS记录号WOS:000252715400014
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/1965
专题植物化学与西部植物资源持续利用国家重点实验室
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Yongli Zhang,Fukai Bao,Juanjuan Hu,et al. Antibacterial lignans and triterpenoids from Rostellularia procumbens[J]. PLANTA MEDICA,2007,73(15):1596-1599.
APA Yongli Zhang.,Fukai Bao.,Juanjuan Hu.,Shengwang Liang.,YuZhang.,...&Yongxian Cheng.(2007).Antibacterial lignans and triterpenoids from Rostellularia procumbens.PLANTA MEDICA,73(15),1596-1599.
MLA Yongli Zhang,et al."Antibacterial lignans and triterpenoids from Rostellularia procumbens".PLANTA MEDICA 73.15(2007):1596-1599.
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