Three new polyyne (= polyacetylene) glucosides from the edible roots of Codonopsis cordifolioidea
Mei, Ren-Qiang1,2; Lu, Qing1; Hu, Yan-Fen1; Liu, Hai-Yang1; Bao, Fu-Kai3; Zhang, Yu3; Cheng, Yong-Xian1
2008
Source PublicationHELVETICA CHIMICA ACTA
ISSN0018-019X
Volume91Issue:1Pages:90-96
Abstract

Three new linear C-14 polyyne (= polyacetylene) glucosides, cordifolioidynes A-C (1-3), together with two known polyynes, lobetyol (4) and lobetyolin (5), and five known phenylpropanoids, i.e., sinapinaldehyde (6), coniferaldehyde (7), coniferoside (8), sachaliside (9), and isoconiferin (10), were isolated from the roots of Codonopsis cordifolioidea. The structures of 1-3 were established from spectral evidences and by characterization of their hydrolysis products. Acid hydrolysis of I afforded the aglycone la, while hydrolysis of 2 and 3 gave the cyclization products 2a and 3a, respectively. Compounds 4-10 were isolated from this plant for the first time. The antibacterial activity of compounds 1-5 were assessed against eight microbial strains by the agar dilution method, none of them exhibited antibacterial effects at concentrations up to 100 mu g/ml.

KeywordCampanulaceae Plant Family Phenylpropanoid Glycosides Natural Acetylenes Tetrahydropyranyl Alcohols
Subject AreaChemistry ; Multidisciplinary
Indexed BySCI ; IC
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000252874800011
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/1927
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Kunming Med Coll, Dept Microbiol & Immunol, Kunming 650031, Peoples R China
Recommended Citation
GB/T 7714
Mei, Ren-Qiang,Lu, Qing,Hu, Yan-Fen,et al. Three new polyyne (= polyacetylene) glucosides from the edible roots of Codonopsis cordifolioidea[J]. HELVETICA CHIMICA ACTA,2008,91(1):90-96.
APA Mei, Ren-Qiang.,Lu, Qing.,Hu, Yan-Fen.,Liu, Hai-Yang.,Bao, Fu-Kai.,...&Cheng, Yong-Xian.(2008).Three new polyyne (= polyacetylene) glucosides from the edible roots of Codonopsis cordifolioidea.HELVETICA CHIMICA ACTA,91(1),90-96.
MLA Mei, Ren-Qiang,et al."Three new polyyne (= polyacetylene) glucosides from the edible roots of Codonopsis cordifolioidea".HELVETICA CHIMICA ACTA 91.1(2008):90-96.
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