Kadcotriones A-C: Tricyclic Triterpenoids from Kadsura coccinea
Liang, Cheng-Qin1,2,4; Shi, Yi-Ming1,4; Li, Xing-Yao1,4; Luo, Rong-Hua3,4; Li, Yan1; Zheng, Yong-Tang3; Zhang, Hong-Bin2; Xiao, Wei-Lie1; Sun, Han-Dong1
AbstractThree new triterpenoids, kadcotriones A-C (1-3), together with the biogenetically related lanostane-type triterpenoid (4), were isolated from Kadsura coccinea. Compound 1 features a 12,14 beta-dimethyl 6/6/6-fused tricyclic skeleton, while 2 and 3 are characterized by a 6/6/5-ring system. Their structures were determined by NMR and electronic circular dichroism spectroscopic methods. Compounds 2 and 4 exhibited anti-HIV-1 activities with EC50 values of 30.29 and 54.81 mu M, respectively.
Indexed BySCI ; IC
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000329331200024
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Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Yunnan, Peoples R China
3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Chinese Acad Sci & Yunnan Prov, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Liang, Cheng-Qin,Shi, Yi-Ming,Li, Xing-Yao,et al. Kadcotriones A-C: Tricyclic Triterpenoids from Kadsura coccinea[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(12):2350-2354.
APA Liang, Cheng-Qin.,Shi, Yi-Ming.,Li, Xing-Yao.,Luo, Rong-Hua.,Li, Yan.,...&Sun, Han-Dong.(2013).Kadcotriones A-C: Tricyclic Triterpenoids from Kadsura coccinea.JOURNAL OF NATURAL PRODUCTS,76(12),2350-2354.
MLA Liang, Cheng-Qin,et al."Kadcotriones A-C: Tricyclic Triterpenoids from Kadsura coccinea".JOURNAL OF NATURAL PRODUCTS 76.12(2013):2350-2354.
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