中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Indole Alkaloids with New Skeleton Activating Neural Stem Cells
作者: Yang, Xing-Wei1, 3; Yang, Cui-Ping2; Jiang, Li-Ping2, 3; Qin, Xu-Jie1, 3; Liu, Ya-Ping1; Shen, Qiu-Shuo2, 3; Chen, Yong-Bin2; null(罗晓东)1
刊名: ORGANIC LETTERS
关键词: ENIGMATIC RELATIONSHIPS ; BAYESIAN PHYLOGENETICS ; EVOLUTIONARY HISTORY ; C-4 PHOTOSYNTHESIS ; PLASTID GENOMES ; GRASSES POACEAE ; TREE SELECTION ; WOODY BAMBOOS ; MIXED MODELS ; NUCLEAR LOCI ; Branch length ; chloroplast phylogenomics ; data partitioning ; low sequence divergence ; sampling ; temperate woody bamboos
英文摘要: Alstoscholarisines A-E (1-5), five unprecedented monoterpenoid indole alkaloids with 6/5/6/6/6 fused-bridge rings, were isolated from Alstonia scholaris. They promoted adult neuronal stem cells (NSCs) proliferation significantly, in which the most active one (1) functioned from a concentration of 0.1 rho g/mL in a dosage-dependent manner. Furthermore, 1 enhanced NSC sphere formation and neurogenic fate commitment through activation of a Wnt signaling pathway and promoted NSC differentiation but did not affect proliferation of neuroblastoma cells.
出版日期: 2014-11-07
卷号: 16, 期号:21, 页码:5808-5811
DOI标识: 10.1021/ol5029223
语种: 英语
ISSN号: 1523-7060
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/18456
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Yang-2014-Indole Alkaloids with New Skeleton A.pdf(312KB)----开放获取View 联系获取全文

作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mechanisms, Kunming 650223, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China

Recommended Citation:
Yang,Xing-Wei;Yang,Cui-Ping;Jiang,Li-Ping;Qin,Xu-Jie;Liu,Ya-Ping;Shen,Qiu-Shuo;Chen,Yong-Bin;Luo,Xiao-Dong.Indole Alkaloids with New Skeleton Activating Neural Stem Cells,ORGANIC LETTERS,2014,68(1):159-238
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yang, Xing-Wei]'s Articles
[Yang, Cui-Ping]'s Articles
[Jiang, Li-Ping]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yang, Xing-Wei]‘s Articles
[Yang, Cui-Ping]‘s Articles
[Jiang, Li-Ping]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Yang-2014-Indole Alkaloids with New Skeleton A.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace