中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 资源植物与生物技术所级重点实验室  > 期刊论文
题名: Chemical constituents from Euphorbia stracheyi and their biological activities
作者: Yang, Da-Song1; Peng, Wei-Bing2; Li, Zi-Lei1; Wang, Xue2; Wei, Jian-Guo1; He, Qiu-Xia2; Yang Yongping(杨永平)1; Liu, Ke-Chun2; Li, Xiao-Li1
刊名: FITOTERAPIA
出版日期: 2014-09-01
卷号: 97, 页码:211-218
关键词: Euphorbia stracheyi ; Euphorbiaceae ; Diterpenoid ; Sesquiterpene ; Cytotoxicity
学科分类: Pharmacology & Pharmacy
DOI: 10.1016/j.fitote.2014.06.013
通讯作者: Li,XL (reprint author),Chinese Acad Sci,Kunming Inst Bot,Inst Tibetan Plateau Res Kunming,Key Lab Econ Plants & Biotechnol,Germplasm Bank W,Kunming 650201,Peoples R China. ; li_xiaoli11@mail.kib.ac.cn
文章类型: Article
英文摘要: Three new diterpenoids, stracheyioids A-C (1-3), as well as 36 known compounds (4-39) were isolated from the whole plants of Euphorbia stracheyi. Compound 1 was a rare 13-deoxy tigliane diterpenoid and compound 2 was an ingenol diterpenoid characterized by an unique 2Z,4Z-decadienoyl acidic moieties. All the known compounds were isolated from E. stracheyi for the first time. Their structures were elucidated on the basis of extensive spectroscopic interpretation. Compounds 1-39 were tested for their cytotoxicity against five cancer cell lines (A-549, MCF-7, Hep G2, Hela and P388) and showed IC50 values in the range 6.64-42.86 mu M. The antiangiogenic activities of the isolated compounds were also evaluated using a zebrafish model. (C) 2014 Elsevier B.V. All rights reserved.
类目[WOS]: Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: C-13 NMR-SPECTROSCOPY ; PHORBOL ESTERS ; DITERPENES ; GLYCOSIDES ; FISCHERIANA ; DERIVATIVES ; LATHYRANE ; PLANTS ; ROOTS ; OIL
收录类别: SCI
语种: 英语
WOS记录号: WOS:000341346400027
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/18407
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Yang-2014-Chemical constituent.pdf(439KB)----开放获取View Download

作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, Inst Tibetan Plateau Res Kunming, Key Lab Econ Plants & Biotechnol,Germplasm Bank W, Kunming 650201, Peoples R China
2.Shandong Acad Sci, Inst Biol, Jinan 250014, Peoples R China

Recommended Citation:
Yang,Da-Song;Peng,Wei-Bing;Li,Zi-Lei;Wang,Xue;Wei,Jian-Guo;He,Qiu-Xia;Yang,Yong-Ping;Liu,Ke-Chun;Li,Xiao-Li.Chemical constituents from Euphorbia stracheyi and their biological activities,FITOTERAPIA,2014,97():211-218
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yang, Da-Song]'s Articles
[Peng, Wei-Bing]'s Articles
[Li, Zi-Lei]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yang, Da-Song]‘s Articles
[Peng, Wei-Bing]‘s Articles
[Li, Zi-Lei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Yang-2014-Chemical constituent.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace