Seven new phragmalin limonoids, chukvelutilides I-O (1-7), were isolated from the stem barks of Chukrasia tabularis var. velutina. Their structures were elucidated by extensive spectroscopic analy-sis. Among them, compound 1 showed moderate lethal activity against brine shrimp larvae, with an LC50 value of 84.1 mu M.
1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Dept Biogeog & Ecol, Kunming 650201, Peoples R China 4.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Structure Based Drug Design & Discovery, Shenyang, Peoples R China
Yin,Jun-Lin;Fang,Xin;Liu,En-De;Yuan,Chun-Mao;Li,Shi-Fei;Zhang,Yu;He,Hong-Ping;Li,Shun-Lin;Di,Ying-Tong;Hao,Xiao-Jiang.Phragmalin Limonoids from the Stem Barks of Chukrasia tabularis var. velutina,PLANTA MEDICA,2014,80(15):1304-1309