| Aspergillines A-E, Highly Oxygenated Hexacyclic Indole-Tetrahydrofuran-Tetramic Acid Derivatives from Aspergillus versicolor | |
| Zhou, Min1,2,3; Miao, Ming-Ming1; Du, Gang2,3; Li, Xiao-Nian4; Shang, Shan-Zhai1; Zhao, Wei1; Liu, Zhi-Hua1; Yang, Guang-Yu1; Che, Chun-Tao5,6; Hu, Qiu-Fen1; Gao, Xue-Mei1,2,3; Hu,QF (reprint author),China Tobacco Yunnan Ind Co Ltd,Key Lab Tobacco Chem Yunnan Prov,Kunming 650231,Peoples R China.; huqiufena@aliyun.com; gao_xuemei@hotmail.com | |
| 2014-10-03 | |
| 发表期刊 | ORGANIC LETTERS
 |
| ISSN | 1523-7060 |
| 卷号 | 16期号:19页码:5016-5019 |
| 摘要 | Aspergillines A-E (1-5) are highly oxygenated cyclopiazonic acid (CPA)-derived alkaloids bearing a rigid and sterically congested hexacyclic indole-tetrahydrofuran-tetramate scaffold, isolated from the endophytic fungus Aspergillus vesicolor. Apergillines A-C represent a new subclass of CPA-derived alkaloids, and aspergillines B and E possess a butanoic acid methyl ester moiety. The structures, including absolute configuration, were elucidated by interpretation of the NMR, X-ray crystallographic, and circular dichroism data. All compounds displayed anti-TMV and cytotoxic activities. |
| 关键词 | Cyclopiazonic Acid Biological-activity Biosynthesis Flavus |
| 学科领域 | Chemistry |
| DOI | 10.1021/ol502307u |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000342719500013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18376 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Hu,QF (reprint author),China Tobacco Yunnan Ind Co Ltd,Key Lab Tobacco Chem Yunnan Prov,Kunming 650231,Peoples R China.; huqiufena@aliyun.com; gao_xuemei@hotmail.com |
| 作者单位 | 1.China Tobacco Yunnan Ind Co Ltd, Key Lab Tobacco Chem Yunnan Prov, Kunming 650231, Peoples R China 2.Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Yunnan, Peoples R China 3.Yunnan Univ Nationalities, Minist Educ, Kunming 650031, Yunnan, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 5.Univ Illinois, Dept Med Chem & Pharmacognosy, Coll Pharm, Chicago, IL 60612 USA 6.Univ Illinois, WHO Collaborating Ctr Tradit Med, Coll Pharm, Chicago, IL 60612 USA |
| 推荐引用方式 GB/T 7714 | Zhou, Min,Miao, Ming-Ming,Du, Gang,et al. Aspergillines A-E, Highly Oxygenated Hexacyclic Indole-Tetrahydrofuran-Tetramic Acid Derivatives from Aspergillus versicolor[J]. ORGANIC LETTERS,2014,16(19):5016-5019. |
| APA | Zhou, Min.,Miao, Ming-Ming.,Du, Gang.,Li, Xiao-Nian.,Shang, Shan-Zhai.,...&gao_xuemei@hotmail.com.(2014).Aspergillines A-E, Highly Oxygenated Hexacyclic Indole-Tetrahydrofuran-Tetramic Acid Derivatives from Aspergillus versicolor.ORGANIC LETTERS,16(19),5016-5019. |
| MLA | Zhou, Min,et al."Aspergillines A-E, Highly Oxygenated Hexacyclic Indole-Tetrahydrofuran-Tetramic Acid Derivatives from Aspergillus versicolor".ORGANIC LETTERS 16.19(2014):5016-5019. |
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