Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp. | |
Wu, Shao-Hua1; He, Jian2; Li, Xiao-Nian3; Huang, Rong4; Song, Fei1; Chen, You-Wei1; Miao, Cui-Ping1; Wu, SH (reprint author), Yunnan Univ, Yunnan Inst Microbiol, Key Lab Microbial Resources, Minist Educ, Kunming 650091, Peoples R China.; shwu123@126.com; jianhe2005@gmail.com | |
2014-09-01 | |
发表期刊 | PHYTOCHEMISTRY |
ISSN | 0031-9422 |
卷号 | 105页码:197-204 |
摘要 | Nine oxygenated guaiane-type sesquiterpenes and three isopimarane diterpenes were isolated from the culture broth of an endophytic fungus. Xylaria sp. YM 311647, obtained from Azadirachta indica. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configurations of two of these were confirmed by X-ray crystallographic analysis. All of the compounds were tested for their antifungal activities against five pathogenic fungal cells. The results showed that nine sesquiterpenes were moderately active against Candida albicans and Hormodendrum compactum with MIC values ranging from 32 to 256 mu g/ml, while the diterpenes were more active; One of these exhibited the most potent inhibitory activity against C albicans and Pyricularia olyzae with MIC values of 16 mu g/ml. (C) 2014 Elsevier Ltd. All rights reserved. |
关键词 | Azadirachta Indica Xylaria Sp. Sesquiterpene Diterpene Guaiane Isopimarane Antifungal Activity |
学科领域 | Biochemistry & Molecular Biology ; Plant Sciences |
DOI | 10.1016/j.phytochem.2014.04.016 |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000340986900025 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/18273 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
通讯作者 | Wu, SH (reprint author), Yunnan Univ, Yunnan Inst Microbiol, Key Lab Microbial Resources, Minist Educ, Kunming 650091, Peoples R China.; shwu123@126.com; jianhe2005@gmail.com |
作者单位 | 1.Yunnan Univ, Yunnan Inst Microbiol, Key Lab Microbial Resources, Minist Educ, Kunming 650091, Peoples R China 2.Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 4.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Peoples R China |
推荐引用方式 GB/T 7714 | Wu, Shao-Hua,He, Jian,Li, Xiao-Nian,et al. Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp.[J]. PHYTOCHEMISTRY,2014,105:197-204. |
APA | Wu, Shao-Hua.,He, Jian.,Li, Xiao-Nian.,Huang, Rong.,Song, Fei.,...&jianhe2005@gmail.com.(2014).Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp..PHYTOCHEMISTRY,105,197-204. |
MLA | Wu, Shao-Hua,et al."Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp.".PHYTOCHEMISTRY 105(2014):197-204. |
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