Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp.
Wu, Shao-Hua1; He, Jian2; Li, Xiao-Nian3; Huang, Rong4; Song, Fei1; Chen, You-Wei1; Miao, Cui-Ping1; Wu, SH (reprint author), Yunnan Univ, Yunnan Inst Microbiol, Key Lab Microbial Resources, Minist Educ, Kunming 650091, Peoples R China.; shwu123@126.com; jianhe2005@gmail.com
2014-09-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号105页码:197-204
产权排序第三
摘要Nine oxygenated guaiane-type sesquiterpenes and three isopimarane diterpenes were isolated from the culture broth of an endophytic fungus. Xylaria sp. YM 311647, obtained from Azadirachta indica. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configurations of two of these were confirmed by X-ray crystallographic analysis. All of the compounds were tested for their antifungal activities against five pathogenic fungal cells. The results showed that nine sesquiterpenes were moderately active against Candida albicans and Hormodendrum compactum with MIC values ranging from 32 to 256 mu g/ml, while the diterpenes were more active; One of these exhibited the most potent inhibitory activity against C albicans and Pyricularia olyzae with MIC values of 16 mu g/ml. (C) 2014 Elsevier Ltd. All rights reserved.
关键词Azadirachta Indica Xylaria Sp. Sesquiterpene Diterpene Guaiane Isopimarane Antifungal Activity
资助信息National Natural Science Foundation of China [21062027, 20772105, 20502021]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2008PY028]; Natural Science Foundation of Yunnan Province [2010CD009]
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytochem.2014.04.016
收录类别SCI ; IC
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000340986900025
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18273
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Wu, SH (reprint author), Yunnan Univ, Yunnan Inst Microbiol, Key Lab Microbial Resources, Minist Educ, Kunming 650091, Peoples R China.; shwu123@126.com; jianhe2005@gmail.com
作者单位1.Yunnan Univ, Yunnan Inst Microbiol, Key Lab Microbial Resources, Minist Educ, Kunming 650091, Peoples R China
2.Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
4.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Peoples R China
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Wu, Shao-Hua,He, Jian,Li, Xiao-Nian,et al. Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp.[J]. PHYTOCHEMISTRY,2014,105:197-204.
APA Wu, Shao-Hua.,He, Jian.,Li, Xiao-Nian.,Huang, Rong.,Song, Fei.,...&jianhe2005@gmail.com.(2014).Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp..PHYTOCHEMISTRY,105,197-204.
MLA Wu, Shao-Hua,et al."Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp.".PHYTOCHEMISTRY 105(2014):197-204.
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