| Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr | |
Huang, Sheng-Zhuo1,2; Zhang, Xuan3; Ma, Qing-Yun1; Peng, Hua2 ; Zheng, Yong-Tang3; Hu, Jiang-Miao2; Dai, Hao-Fu1; Zhou, Jun2; Zhao, You-Xing1; Zhou,J (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.; junzhou3264@126.com; zhaoyx1011@163.com
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| 2014-06-01 | |
| 发表期刊 | FITOTERAPIA
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| ISSN | 0367-326X |
| 卷号 | 95页码:34-41 |
| 摘要 | Three tigliane-type diterpenoids named excoecafolins A-C and two daphnane-type diterpenoids named excoecafolins D and E, together with 13 known compounds, were isolated from the EtOAc extract of Excoecaria acerzfolia Didr. Their structures were elucidated through the analysis of the spectroscopic data. The anti-HIV-1 activity evaluation of five of these compounds showed that four possessed moderate anti-HIV-1 activities with EC50 0.258, 0.036, 0.046, and 0.978 mu M, SI >1,836.9,431.1, 298.7, and >503.7, respectively. Additionally, the chemotaxonomic issue of the affinity correlation between Thymelaeceae and Euphorbiaceae is discussed based on the isolates. (C) 2014 Elsevier B.V. All rights reserved. |
| 关键词 | Excoecaria Acerifolia Euphorbiaceae Excoecafolin Anti-hiv-1 Chemotaxonomy |
| 学科领域 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1016/j.fitote.2014.02.018 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000336819400005 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18187 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Zhou,J (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.; junzhou3264@126.com; zhaoyx1011@163.com |
| 作者单位 | 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Sheng-Zhuo,Zhang, Xuan,Ma, Qing-Yun,et al. Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr[J]. FITOTERAPIA,2014,95:34-41. |
| APA | Huang, Sheng-Zhuo.,Zhang, Xuan.,Ma, Qing-Yun.,Peng, Hua.,Zheng, Yong-Tang.,...&zhaoyx1011@163.com.(2014).Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr.FITOTERAPIA,95,34-41. |
| MLA | Huang, Sheng-Zhuo,et al."Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr".FITOTERAPIA 95(2014):34-41. |
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| Huang-2014-Anti-HIV-（758KB） | 开放获取 | CC BY-NC-SA | 浏览 下载 | |||
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