New Acylphloroglucinol Derivatives with Diverse Architectures from Hypericum henryi
Yang, Xing-Wei1,3; Ding, Yuanqing2; Zhang, Jing-Jing1,3; Liu, Xia1,3; Yang, Li-Xin1; Li, Xiao-Nian1; Ferreira, Daneel2; Walker, Larry A.2; Xu, Gang1
通讯作者Xu,G (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; xugang008@mail.kib.ac.cn
2014-05-02
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号16期号:9页码:2434-2437
摘要Hyphenrones A-F (1-6), six polycyclic polyprenylated acylphloroglucinol derivatives with four architectures including three unprecedented cores as exemplified by 1, 3, and 4, were isolated from Hypericum henryi. Compounds 3 and 4 possess two unique 5/8/5 and 6/6/5/8/5 fused ring systems, respectively. Their absolute configurations were defined by experimental and calculated ECD of 4 and X-ray diffractions of 5 and 6, coupled with their putative biosynthetic origins. Three compounds exhibited interesting AChE inhibitory activities.
关键词Electronic Circular-dichroism Polycyclic Polyprenylated Acylphloroglucinols Hyperforin Perforatum Cohaerens Core
学科领域Chemistry
DOI10.1021/ol500808p
收录类别SCI ; IC
语种英语
WOS记录号WOS:000335491000035
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18113
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Mississippi, Sch Pharm, Pharmaceut Sci Res Inst, Natl Ctr Nat Prod Res,Dept Pharmacognosy, University, MS 38677 USA
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Yang, Xing-Wei,Ding, Yuanqing,Zhang, Jing-Jing,et al. New Acylphloroglucinol Derivatives with Diverse Architectures from Hypericum henryi[J]. ORGANIC LETTERS,2014,16(9):2434-2437.
APA Yang, Xing-Wei.,Ding, Yuanqing.,Zhang, Jing-Jing.,Liu, Xia.,Yang, Li-Xin.,...&Xu, Gang.(2014).New Acylphloroglucinol Derivatives with Diverse Architectures from Hypericum henryi.ORGANIC LETTERS,16(9),2434-2437.
MLA Yang, Xing-Wei,et al."New Acylphloroglucinol Derivatives with Diverse Architectures from Hypericum henryi".ORGANIC LETTERS 16.9(2014):2434-2437.
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