| Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa | |
Zhang, Xu-Dong1,2; Ni, Wei1; Yan, Huan1; Li, Gen-Tao1; Zhong, Hui-Min2; Li, Yan1 ; Liu, Hai-Yang1
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| 通讯作者 | Liu,HY (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; haiyangliu@mail.kib.ac.cn |
| 2014-05-01 | |
| 发表期刊 | CHEMISTRY & BIODIVERSITY
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| ISSN | 1612-1872 |
| 卷号 | 11期号:5页码:760-766 |
| 摘要 | Phytochemical investigation of whole plants of Euphorbia pilosa led to the isolation and identification of two new daphnane-diterpenoid glucosides, euphopilosides A and B (1 and 2, resp.), and a new ent-abietane, euphopilolide (3), together with eight known compounds. Compounds 1 and 2 are the first daphnane-type diterpenoid glycosides. Their structures were elucidated by a combination of 1D- and 2D-NMR, and MS analyses, and acid hydrolysis. Compounds 1-9 were evaluated for their in vitro cytotoxicities against five human tumor cell lines, HL-60, SMMC-7721, A-549, MCF-7, and SW-480. Compound 7 showed moderate inhibitory activity against all five cell lines. |
| 关键词 | Euphorbia Pilosa Diterpenoids Daphnane Glycosides Cytotoxic Activity |
| 学科领域 | Biochemistry & Molecular Biology ; Chemistry |
| DOI | 10.1002/cbdv.201300154 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000336376200007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18105 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xu-Dong,Ni, Wei,Yan, Huan,et al. Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa[J]. CHEMISTRY & BIODIVERSITY,2014,11(5):760-766. |
| APA | Zhang, Xu-Dong.,Ni, Wei.,Yan, Huan.,Li, Gen-Tao.,Zhong, Hui-Min.,...&Liu, Hai-Yang.(2014).Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa.CHEMISTRY & BIODIVERSITY,11(5),760-766. |
| MLA | Zhang, Xu-Dong,et al."Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa".CHEMISTRY & BIODIVERSITY 11.5(2014):760-766. |
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