Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa
Zhang, Xu-Dong1,2; Ni, Wei1; Yan, Huan1; Li, Gen-Tao1; Zhong, Hui-Min2; Li, Yan1; Liu, Hai-Yang1
Corresponding AuthorLiu,HY (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; haiyangliu@mail.kib.ac.cn
2014-05-01
Source PublicationCHEMISTRY & BIODIVERSITY
ISSN1612-1872
Volume11Issue:5Pages:760-766
AbstractPhytochemical investigation of whole plants of Euphorbia pilosa led to the isolation and identification of two new daphnane-diterpenoid glucosides, euphopilosides A and B (1 and 2, resp.), and a new ent-abietane, euphopilolide (3), together with eight known compounds. Compounds 1 and 2 are the first daphnane-type diterpenoid glycosides. Their structures were elucidated by a combination of 1D- and 2D-NMR, and MS analyses, and acid hydrolysis. Compounds 1-9 were evaluated for their in vitro cytotoxicities against five human tumor cell lines, HL-60, SMMC-7721, A-549, MCF-7, and SW-480. Compound 7 showed moderate inhibitory activity against all five cell lines.
KeywordEuphorbia Pilosa Diterpenoids Daphnane Glycosides Cytotoxic Activity
Subject AreaBiochemistry & Molecular Biology ; Chemistry
DOI10.1002/cbdv.201300154
Indexed BySCI
Language英语
WOS IDWOS:000336376200007
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/18105
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Xu-Dong,Ni, Wei,Yan, Huan,et al. Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa[J]. CHEMISTRY & BIODIVERSITY,2014,11(5):760-766.
APA Zhang, Xu-Dong.,Ni, Wei.,Yan, Huan.,Li, Gen-Tao.,Zhong, Hui-Min.,...&Liu, Hai-Yang.(2014).Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa.CHEMISTRY & BIODIVERSITY,11(5),760-766.
MLA Zhang, Xu-Dong,et al."Daphnane-Type Diterpenoid Glucosides and Further Constituents of Euphorbia pilosa".CHEMISTRY & BIODIVERSITY 11.5(2014):760-766.
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