Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma
Dong, Ke1,2; Pu, Jian-Xin1; Du, Xue1; Su, Jia1; Li, Xiao-Nian1; Yang, Jian-Hong1; Zhao, Wei3; Li, Yan1; Sun, Han-Dong1
Corresponding AuthorPu, JX (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
2012-06-17
Source PublicationTETRAHEDRON
ISSN0040-4020
Volume68Issue:24Pages:4820-4829
AbstractFourteen new lanostane triterpene acids (1-14), and five known analogues (15-19) were isolated from the stems of Kadsura polysperma. Compound 1, with a rearranged tetracyclic skeleton, is an important biogenic precursor of longipedlactone skeleton. Compounds 2-6 are members of 18(13 -> 12)-abeo-lanostane triterpene acids. The structures of new compounds were elucidated by spectroscopic evidence. Selected compounds were evaluated for their in vitro cytotoxicity against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. (C) 2012 Elsevier Ltd. All rights reserved.
KeywordKadsura Polysperma Lanostane Triterpene Acid Kadpolysperins Cytotoxicity
Subject AreaChemistry
DOI10.1016/j.tet.2012.03.116
Indexed BySCI ; IC
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000304798800031
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/17619
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Yunnan Acad Tobacco Sci, Kunming 650106, Peoples R China
Recommended Citation
GB/T 7714
Dong, Ke,Pu, Jian-Xin,Du, Xue,et al. Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma[J]. TETRAHEDRON,2012,68(24):4820-4829.
APA Dong, Ke.,Pu, Jian-Xin.,Du, Xue.,Su, Jia.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2012).Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma.TETRAHEDRON,68(24),4820-4829.
MLA Dong, Ke,et al."Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma".TETRAHEDRON 68.24(2012):4820-4829.
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