Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma
Dong, Ke1,2; Pu, Jian-Xin1; Du, Xue1; Su, Jia1; Li, Xiao-Nian1; Yang, Jian-Hong1; Zhao, Wei3; Li, Yan1; Sun, Han-Dong1
2012-06-17
发表期刊TETRAHEDRON
ISSN0040-4020
卷号68期号:24页码:4820-4829
摘要Fourteen new lanostane triterpene acids (1-14), and five known analogues (15-19) were isolated from the stems of Kadsura polysperma. Compound 1, with a rearranged tetracyclic skeleton, is an important biogenic precursor of longipedlactone skeleton. Compounds 2-6 are members of 18(13 -> 12)-abeo-lanostane triterpene acids. The structures of new compounds were elucidated by spectroscopic evidence. Selected compounds were evaluated for their in vitro cytotoxicity against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. (C) 2012 Elsevier Ltd. All rights reserved.
关键词Kadsura Polysperma Lanostane Triterpene Acid Kadpolysperins Cytotoxicity
资助信息This work was supported financially by the NSFC (No. 30830115 to H.-D.S., and 20902093 to J.-X.P.), the Science and Technology Program of Yunnan Province (2008GA031), the Major State Basic Research Development Program of China (No. 2009CB522300), the Western Doctoral Foundation of Chinese Academy of Sciences (J.-X.P.), and the Reservation-Talent Project of Yunnan Province (J.-X.P.).
学科领域Chemistry
DOI10.1016/j.tet.2012.03.116
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000304798800031
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/17619
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Yunnan Acad Tobacco Sci, Kunming 650106, Peoples R China
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GB/T 7714
Dong, Ke,Pu, Jian-Xin,Du, Xue,et al. Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma[J]. TETRAHEDRON,2012,68(24):4820-4829.
APA Dong, Ke.,Pu, Jian-Xin.,Du, Xue.,Su, Jia.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2012).Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma.TETRAHEDRON,68(24),4820-4829.
MLA Dong, Ke,et al."Kadpolysperins A-N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma".TETRAHEDRON 68.24(2012):4820-4829.
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