Biogenetically related caged ent-kaurane diterpenoids from Isodon eriocalyx var. laxiflora

doi:10.1016/j.tetlet.2012.03.112

	Biogenetically related caged ent-kaurane diterpenoids from Isodon eriocalyx var. laxiflora
	Wang, Wei-Guang 1,2; Li, Xiao-Nian 1; Du, Xue 1; Dong, Ke 1; Zhao, Wei 1; Wu, Hai-Yan 1; Kong, Ling-Mei 1; Li, Yan1 ; Pu, Jian-Xin1 ; Sun, Han-Dong1
通讯作者	Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
	2012-05-30
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	53 期号:22 页码:2777-2781
摘要	Two novel caged ent-kauranoids, neolaxiflorins D (1) and E (2), along with three other new ent-kauranoids, neolaxiflorins F-H (3-5), and a known one, eriocalyxin B (6), were obtained from lsodon eriocalyx var. laxiflora. Neolaxiflorin D (1) is the first 15,16-seco-16,17-dinor-ent-kaurane diterpenoid, and neolaxiflorin E (2) is the first 15,16-seco-17-homo-ent-kauranoid. The absolute configurations of ent-kauranoids 1 and 2 were determined by single-crystal X-ray diffraction analyses. Structural analysis of intermediate compounds 3-5 indicated that eriocalyxin B (6) is a biogenetic precursor of caged ent-kauranoids 1 and 2 as illustrated. The cytotoxic activity of the new compounds was evaluated by an MIT assay. (C) 2012 Elsevier Ltd. All rights reserved.
关键词	Caged Diterpenoid Ent-kaurane Isodon Eriocalyx Var. Laxiflora
学科领域	Chemistry
DOI	10.1016/j.tetlet.2012.03.112
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000303953200027
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/17609
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Wang, Wei-Guang,Li, Xiao-Nian,Du, Xue,et al. Biogenetically related caged ent-kaurane diterpenoids from Isodon eriocalyx var. laxiflora[J]. TETRAHEDRON LETTERS,2012,53(22):2777-2781.
APA	Wang, Wei-Guang.,Li, Xiao-Nian.,Du, Xue.,Dong, Ke.,Zhao, Wei.,...&Sun, Han-Dong.(2012).Biogenetically related caged ent-kaurane diterpenoids from Isodon eriocalyx var. laxiflora.TETRAHEDRON LETTERS,53(22),2777-2781.
MLA	Wang, Wei-Guang,et al."Biogenetically related caged ent-kaurane diterpenoids from Isodon eriocalyx var. laxiflora".TETRAHEDRON LETTERS 53.22(2012):2777-2781.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Wang-2012-Biogenetic（662KB）			开放获取	CC BY-NC-SA	浏览下载