| Laxiflorolides A and B, Epimeric Bishomoditerpene Lactones from Isodon eriocalyx | |
Wang, Wei-Guang1,2; Li, Xiao-Nian1; Du, Xue1; Wu, Hai-Yan1; Liu, Xu1; Su, Jia1; Li, Yan1 ; Pu, Jian-Xin1; Sun, Han-Dong1
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| 通讯作者 | Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn |
| 2012-06-01 | |
| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
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| ISSN | 0163-3864 |
| 卷号 | 75期号:6页码:1102-1107 |
| 摘要 | Laxiflorolides A (1) and B (2), two unprecedented epimeric bishomoditerpene lactones with a unique C-22 framework, along with laxiflorins P-R (3-5), maoecrystal P (6), maoecrystal C (7), and eriocalyxin B (8), were isolated from the leaves of I. eriocalyx var. laxiflora. The structures of 1 and 2, including the absolute configurations, were determined by spectroscopic methods and single-crystal X-ray diffraction analysis. All of the compounds isolated were evaluated for their cytotoxicity against five tumor cell lines. Compounds 3, 6, and 8 showed remarkable cytotoxic activity against certain cell lines compared with the positive control. |
| 关键词 | Ent-kaurane Diterpenoids Var. Laxiflora Leukemic-cells Cytotoxicity Induction Differentiation Antioxidant Macrophages Products Pharicin |
| 学科领域 | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1021/np300106j |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000305503500014 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/17607 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Wei-Guang,Li, Xiao-Nian,Du, Xue,et al. Laxiflorolides A and B, Epimeric Bishomoditerpene Lactones from Isodon eriocalyx[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(6):1102-1107. |
| APA | Wang, Wei-Guang.,Li, Xiao-Nian.,Du, Xue.,Wu, Hai-Yan.,Liu, Xu.,...&Sun, Han-Dong.(2012).Laxiflorolides A and B, Epimeric Bishomoditerpene Lactones from Isodon eriocalyx.JOURNAL OF NATURAL PRODUCTS,75(6),1102-1107. |
| MLA | Wang, Wei-Guang,et al."Laxiflorolides A and B, Epimeric Bishomoditerpene Lactones from Isodon eriocalyx".JOURNAL OF NATURAL PRODUCTS 75.6(2012):1102-1107. |
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