Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius

doi:10.1021/ol401991u

	Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius
	Zhou, Min 1,2; Zhang, Hai-Bo 1; Wang, Wei-Guang 1; Gong, Ning-Bo 3,4; Zhan, Rui 1; Li, Xiao-Nian 1; Du, Xue 1; Li, Li-Mei 5; Li, Yan1 ; Lu, Yang 3,4; Pu, Jian-Xin1 ; Sun, Han-Dong1
通讯作者	Pu,JX (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
	2013-09-06
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	15 期号:17 页码:4446-4449
摘要	Scopariusic acid (1), a new ent-clerodane-based meroditerpenoid with a unique cyclobutane ring and an unusual 1-octen-3-ol substituent, together with its biosynthetic related compound 2, were isolated from the aerial parts of Isodon scoparius. The structures of 1 and 2, including their absolute configurations, were determined by spectroscopic methods, single-crystal X-ray diffraction analysis, and chemical methods. Compound 1 showed weak cytotoxicity and moderate immunosuppressive activity.
关键词	2+2 Cycloadditions Biyouyanagin-a Biological Evaluation Incarvillea-sinensis Revised Structure Skeleton Littoralisone Alkaloids Diterpene
DOI	10.1021/ol401991u
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000328864800044
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/17450
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China 4.Peking Union Med Coll, Beijing 100050, Peoples R China 5.Chengdu Med Coll, Res Ctr, Chengdu, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Min,Zhang, Hai-Bo,Wang, Wei-Guang,et al. Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius[J]. ORGANIC LETTERS,2013,15(17):4446-4449.
APA	Zhou, Min.,Zhang, Hai-Bo.,Wang, Wei-Guang.,Gong, Ning-Bo.,Zhan, Rui.,...&Sun, Han-Dong.(2013).Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius.ORGANIC LETTERS,15(17),4446-4449.
MLA	Zhou, Min,et al."Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius".ORGANIC LETTERS 15.17(2013):4446-4449.

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